Objective: This study is to validate the utilization of Monte Carlo (MC) simulation to model the head of Primus linear accelerator, thereafter, using it to estimate the energy fluence distribution (EFD), the percentage depth dose (PDD), and beam profiles.
Materials And Methods: The BEAM code that is based on the EGS code has been used for modeling the linear accelerator head for 10 MeV electron beam with different applicator sizes (10 × 10, 15 × 15, and 20 × 20 cm ). The phase space was acquired from BEAM at the end of each applicator and then used as an input file to DOSXYZ and BEAMDP to calculate the EFD, PDD, and beam profiles.
Purpose: A method is presented to radiobiologically compare sequential (SEQ) and simultaneously integrated boost (SIB) breast radiotherapy.
Methods: The method is based on identically prescribed biologically effective dose (iso-BED) which was achieved by different prescribed doses due to different fractionation schemes. It is performed by converting the calculated three-dimensional dose distribution to the corresponding BED distribution taking into consideration the different number of fractions for generic α/β ratios.
Purpose: To dosimetrically evaluate different breast SIB techniques with respect to target coverage and organs at risk (OARs) doses.
Methods: Four IMRT techniques were compared in 12 patients. Three techniques employ tangential whole breast irradiation with either two coplanar fields (T-2F), or four non-coplanar fields (T-NC), or one Volumetric Modulated Arc Therapy (T-VMAT) for the boost volume.
Purpose: Second cancer risk after breast conserving therapy is becoming more important due to improved long term survival rates. In this study, we estimate the risks for developing a solid second cancer after radiotherapy of breast cancer using the concept of organ equivalent dose (OED).
Materials And Methods: Computer-tomography scans of 10 representative breast cancer patients were selected for this study.