A retrospective comparison of two different immobilization systems for radiotherapy of extremity soft tissue sarcomas and its influence on CTV-PTV margin.

Background: On account of extremity wide range of movements and difficulty of reproducibility during irradiation of extremity sarcomas, assorted immobilization strategies are employed to eliminate setup errors. The study purpose was to compare the setup errors of the commonly used immobilization tools and to define planning target volume (PTV) margins for each device.

Methods: A retrospective review comparing Vac-Loc™ and thermoplastic cast (Tcast) was conducted.

Modeling the head of PRIMUS linear accelerator for electron-mode at 10 MeV for different applicators.

Objective: This study is to validate the utilization of Monte Carlo (MC) simulation to model the head of Primus linear accelerator, thereafter, using it to estimate the energy fluence distribution (EFD), the percentage depth dose (PDD), and beam profiles.

Materials And Methods: The BEAM code that is based on the EGS code has been used for modeling the linear accelerator head for 10 MeV electron beam with different applicator sizes (10 × 10, 15 × 15, and 20 × 20 cm ). The phase space was acquired from BEAM at the end of each applicator and then used as an input file to DOSXYZ and BEAMDP to calculate the EFD, PDD, and beam profiles.

Outcomes of Early-stage Glottic Carcinoma Treated with Radiation Therapy: A Single Institution Experience.

Objective:  To evaluate the outcomes of radical intent radiation therapy in early glottic carcinoma (EGC), including local control rate (LCR), disease-free survival (DFS), death specific free survival (DSFS), and overall survival (OS) rates, in Saudi patients treated at a single institution.  Materials and methods: This is an institutional review board (IRB) approved, retrospective study of 27 patients with T1-2 N0 M0, early glottic carcinoma (EGC) who were treated from 2010 to 2015 at our institution with different radiotherapy (RT) fractionation regimens. The regimens included six different fractionation schedules of radiotherapy (RT): 50 Gy (20 x 2.

Efficacy of 8 Gy Single Fraction Palliative Radiation Therapy in Painful Bone Metastases: A Single Institution Experience.

Introduction Bone metastasis (BM) is a major complication of many solid tumors like breast, prostate, lung and renal cancers. BM leads to serious sequelae of pain, fractures, spinal cord compression and hypercalcemia. Radiotherapy has an established role in relieving pain caused by BM.

Outcome of patients with glioblastoma in Saudi Arabia: Single center experience.

Glioblastoma multiforme (GBM), the most common primary brain tumor in adults, is associated with one of the worst 5 year survival rates among all human cancer types. To date, no published data are available for the outcome of this disease in Saudi Arabia. The present study performed a single-center, retrospective cohort study to evaluate the outcome of patients with GBM in Saudi Arabia.

Comparison of breast sequential and simultaneous integrated boost using the biologically effective dose volume histogram (BEDVH).

Purpose: A method is presented to radiobiologically compare sequential (SEQ) and simultaneously integrated boost (SIB) breast radiotherapy.

Methods: The method is based on identically prescribed biologically effective dose (iso-BED) which was achieved by different prescribed doses due to different fractionation schemes. It is performed by converting the calculated three-dimensional dose distribution to the corresponding BED distribution taking into consideration the different number of fractions for generic α/β ratios.

Comparison of breast simultaneous integrated boost (SIB) radiotherapy techniques.

Purpose: To dosimetrically evaluate different breast SIB techniques with respect to target coverage and organs at risk (OARs) doses.

Methods: Four IMRT techniques were compared in 12 patients. Three techniques employ tangential whole breast irradiation with either two coplanar fields (T-2F), or four non-coplanar fields (T-NC), or one Volumetric Modulated Arc Therapy (T-VMAT) for the boost volume.

Second cancer risk after 3D-CRT, IMRT and VMAT for breast cancer.

Purpose: Second cancer risk after breast conserving therapy is becoming more important due to improved long term survival rates. In this study, we estimate the risks for developing a solid second cancer after radiotherapy of breast cancer using the concept of organ equivalent dose (OED).

Materials And Methods: Computer-tomography scans of 10 representative breast cancer patients were selected for this study.