Publications by authors named "Moa-Lina Haller"

Article Synopsis
  • * This study analyzed data from over 900 high-risk AF patients to compare outcomes between those receiving LAAO and those getting traditional treatment (mostly oral anticoagulants).
  • * Results showed no significant differences in stroke or cardiovascular death rates, but LAAO patients experienced significantly less clinically relevant bleeding compared to those on conventional treatments.
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Article Synopsis
  • The study assessed eligibility for marine omega-3 fatty acid eicosapentaenoic acid (EPA) supplementation in patients with acute coronary syndromes (ACS) in a Swiss cohort, as recommended by 2019 European Society of Cardiology guidelines.
  • Out of 2643 patients, 32% were eligible for EPA supplementation one year post-ACS, with higher eligibility rates found in younger individuals, smokers, diabetics, hypertensive patients, and the obese.
  • The research indicates that statins and other lipid-lowering therapies could reduce the percentage of these patients eligible for omega-3 supplementation, suggesting a need to address residual cardiovascular risk in those with hypertriglyceridemia.
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Objectives: To assess the association between socioeconomic status (SES) and self-reported adherence to preventive measures in Switzerland during the COVID-19 pandemic.

Methods: 4,299 participants from a digital cohort were followed between September 2020 and November 2021. Baseline equivalised disposable income and education were used as SES proxies.

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Background: Electronic nicotine-delivery systems - also called e-cigarettes - are used by some tobacco smokers to assist with quitting. Evidence regarding the efficacy and safety of these systems is needed.

Methods: In this open-label, controlled trial, we randomly assigned adults who were smoking at least five tobacco cigarettes per day and who wanted to set a quit date to an intervention group, which received free e-cigarettes and e-liquids, standard-of-care smoking-cessation counseling, and optional (not free) nicotine-replacement therapy, or to a control group, which received standard counseling and a voucher, which they could use for any purpose, including nicotine-replacement therapy.

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Background: There is debate over whether statins increase risk of hemorrhagic stroke, so we assessed current evidence, including data from new statin trials and trials of nonstatin low-density lipoprotein-cholesterol (LDL-C)- and triglyceride-lowering therapies.

Methods And Results: We performed a systematic review of large randomized clinical trials (≥1000 patients with ≥2 years follow-up) of LDL-C-lowering therapy (statin, ezetimibe, and PCSK-9 [proprotein convertase subtilisin/kexin type 9] inhibitor) and triglyceride-lowering therapy (omega-3 supplements and fibrate) that reported hemorrhagic stroke as an outcome. We searched MEDLINE, Embase, and Cochrane Library up to July 2, 2021 and updated a meta-analysis of cardiovascular statin trials published in 2012.

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Purpose: We aimed to assess the seroprevalence trends of SARS-CoV-2 antibodies in several Swiss cantons between May 2020 and September 2021 and investigate risk factors for seropositivity and their changes over time.

Methods: We conducted repeated population-based serological studies in different Swiss regions using a common methodology. We defined three study periods: May-October 2020 (period 1, prior to vaccination), November 2020-mid-May 2021 (period 2, first months of the vaccination campaign), and mid-May-September 2021 (period 3, a large share of the population vaccinated).

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SARS-CoV-2 appeared in Switzerland in February 2020 and reached Neuchâtel in March. During 2 months, 43 patients were admitted in the intensive care unit. 55% of ICU admitted patients received mechanical ventilation, 66% of which in prone position.

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