Investigation of phytoconstituents of as potential glucokinase activators through molecular docking for the treatment of type 2 diabetes mellitus.

Glucokinase (GK) is an enzyme involved in synthesising glucose into glucose-6 phosphate and serves a crucial function in glucose sensing. Therefore, agents that induce GK activation could be used to treat T2DM. The present work has been carried out to investigate the GK activation potential of phytoconstituents of through molecular docking.