Silica-Organometallic One-Dimensional Hybrid Employing a Ag-π Bond Connecting Alternating Ag(NO) and Octavinylsilsesquioxane.

Layering AgNO in alcohol onto octavinylsilsesquioxane (OVS) in CHCl results in a one-dimensional coordination polymer, {Ag(NO)(OVS)·solvents} (), consisting of unprecedented flat weakly bonded Ag(NO) alternating with the firmly covalent OVS through Ag-π bonds. The preferential assembling medium for is proven to be alcohols, where a 4:1 silver-OVS adduct is detected by electrospray ionization mass spectrometry. The present outcomes may assist our knowledge of particular interactions for supramolecular architectures of a polynuclear silver system built from OVS containing eight pendent olefin tails.

Therapeutic potential of luteolin in transgenic Drosophila model of Alzheimer's disease.

A transgenic fly line expressing wild type human Aβ42 were exposed to luteolin mixed in diet at final concentration of 5, 10, 15 and 20μM. The climbing assay, activity pattern, life span, aversive phototaxis suppression assay (APS) along with the estimation of protein carbonyl content (PCC), glutathione-S-transferase (GSTs) activity, glutathione (GSH) content, lipid peroxidation (LPO), acetylcholinesterase activity (AChE), superoxide dismutase (SOD) activity, catalase (CAT) activity, caspase 3 and 9 activities in the brain of treated as well as untreated AD flies (Positive control) were studied. Histopathology of Drosophila brain sections was done by performing thioflavin-S, Bielschowsky's silver staining and toluidine blue staining.