Publications by authors named "Mk Sidibe"
Article Synopsis
- - Albinism is caused by a variety of genes (21 identified), with most cases following an autosomal recessive inheritance pattern, though one form is X-linked; about 70% of cases can be diagnosed through genetic analysis.
- - Of the undiagnosed cases, roughly 15% carry one pathogenic variant but may have undiscovered variants in non-coding regions; this research involved sequencing a group of 122 heterozygous patients.
- - From the study, 12 patients received additional diagnoses based on non-coding variants that affected RNA splicing, highlighting the need to investigate non-coding regions to improve diagnostic rates for genetic diseases like albinism.
Albinism is a phenotypically and genetically heterogeneous condition characterized by a variable degree of hypopigmentation and by ocular features leading to reduced visual acuity. Whereas numerous genotypic studies have been conducted throughout the world, very little is known about the genotypic spectrum of albinism in Africa and especially in sub-Saharan Western Africa. Here we report the analysis of all known albinism genes in a series a 23 patients originating from Mali.
View Article and Find Full Text PDFIntroduction: Intravitreal injections (IVT) of a drug aim to rapidly obtain effective concentrations greater than those that would be obtained by a periocular or intravenous injection. The objective of the present study is to demonstrate the contribution of IVT in the treatment of pathologies of the posterior segment of the eye.
Methodology: We conducted a 21-month ambidirectional observational study from January 1, 2020, to September 30, 2021.
A baby born at home 14 hours earlier was brought to the neonatology department with bilateral upper palpebral chemosis with purulent secretions and pseudomembranes, with no general signs of infection. The gram staining of a secretion sample shows the presence of Neisseria gonorrhoeae. Intramuscular ceftriaxone treatment was initiated, combined with topical application of rifamycin, dexamethasone, and oxytetracycline.
View Article and Find Full Text PDFArticle Synopsis
- * A clinical case is presented of a 6-year-old boy with bilateral papillary coloboma who has no other malformations, occurring in a family with two children.
- * The child's background includes a normal birth and current immunization, while his father's and sister's eye exams were normal, although their mother has strabismus in her right eye.
Introduction: Treatment of cataract blindness is surgical to restore vision. The aim of this work was to compare the PKA to the classic EEC in the surgical treatment of adult cataract in terms of anatomical and functional results in our institute.
Materials And Methods: This was a cross-sectional study of 333 operated eyes of cataract of the adult and followed for one month.
Introduction: The treatment of cataract blindness is surgical, allowing restored vision. The purpose of this study was to evaluate the functional results of cataract surgery in adults in a tertiary care referral center.
Patients And Methods: Prospective study of 2012 eyes operated for adult cataract from September 1, 2009 to August 31, 2010 (12 months).