Publications by authors named "Mizuki Sekino"
Thyroid ultrasound examinations (TUEs), conducted as part of the Fukushima Health Management Survey (FHMS), were initiated to monitor the health status of residents after the Fukushima Daiichi Nuclear Power Plant accident owing to concerns regarding the increased incidence of thyroid cancer among children, as observed after the Chernobyl Nuclear Power Plant accident. This study reported the clinicopathological characteristics of patients with thyroid cancer diagnosed through the FHMS and treated at the Fukushima Medical University Hospital. Data regarding the clinicopathological characteristics of patients with thyroid cancer were collected and evaluated in this descriptive study.
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- * It was found that 39.4% of patients had PD-L1 positive expression, which was linked to lower T cell activation (SI levels) and associated with the presence of mutations in 72.7% of patients.
- * The research suggests that high levels of PD-L1, along with CD8+ expression and mutation status, may serve as significant prognostic indicators for survival in thyroid cancer patients, especially in relation to progression-free survival.