Catalytic stereoselective glycosidation with glycosyl diphenyl phosphates: rapid construction of 1,2-cis-alpha-glycosidic linkages.

A commercially available 0.1 M solution of HClO(4) in dioxane has been shown to catalyze the glycosidation of glycosyl diphenyl phosphates. The per-O-benzyl-protected glucosyl and galactosyl donors and the 3,4,6-tri-O-acetyl-2-azido-2-deoxygalactosyl donor each react with a range of acceptor alcohols in the presence of 0.