Publications by authors named "Miyuki Hashiguchi"

Article Synopsis
  • COVID-19, caused by SARS-CoV-2, became a global pandemic, necessitating effective infection control in healthcare settings to identify potential cases.
  • A study involving 1,087 patients in a university hospital isolation ward aimed to identify clinical variables that could help predict COVID-19, using multiple nucleic acid tests for accurate diagnosis.
  • Results showed that out of the participants, 352 (32.4%) were diagnosed with COVID-19, with significant associations found between the virus and factors like age, sex, body mass index, and certain blood markers, suggesting that multiple tests are advisable to confirm or rule out the disease.
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As antibiotic resistance has become a global problem, the intervention of an antimicrobial stewardship team (AST) is warranted. In hematological disorders, infectious complications are crucial owing to abnormal neutrophil function and decreased cell-mediated immunity. Despite the widespread implementation of AST intervention, the effectiveness of stewardship practices for immunocompromised patients remains uncertain.

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Background: As a result of the constant increase in carbapenem resistance amongst gram-negative bacteria in several countries, the inappropriate use of carbapenems must be reduced. Antimicrobial stewardship programmes (ASPs) aim to improve carbapenem usage by implementing interventions, including the promotion of the de-escalation (DE) strategy. Thus, this study aimed to evaluate the impact of this strategy on carbapenem use based on a clear definition of DE.

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