Publications by authors named "Miyu Hosono"
Article Synopsis
- Haploid larvae in non-mammalian vertebrates exhibit lethal growth issues known as 'haploid syndrome,' contrasting with mammals where imprinting misregulation leads to haploid intolerance.
- In an investigation of gynogenetic haploid zebrafish, researchers found that haploid larvae showed premature cell death and mitotic defects due to increased p53 levels, resulting in halted cell division during critical growth stages.
- The study suggests that these cellular issues are critical factors limiting larval growth in haploid conditions, indicating an evolutionary restriction on ploidy levels in vertebrates.
