Publications by authors named "Miyeong Park"

There are no reports comparing diet recovery between patients who underwent distal gastrectomy (DG) and those who underwent total gastrectomy (TG). The aim of the present study was to compare dietary habits and nutritional status after curative treatment with DG and TG in patients with gastric cancer. We retrospectively collected clinical data from 263 consecutive patients who underwent gastrectomy for gastric cancer without recurrence at a single-center between January 2016 and December 2022.

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This study investigates the role of SMARCD3 in gastric cancer by comparing its expression in signet ring cell (SRC) and well-differentiated (WD) groups within gastric cancer cell lines and tissues. We observed elevated SMARCD3 levels in the SRC group compared to the WD group. Functional analysis was conducted through both SMARCD3 knock-in and knock-out methods.

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Background/objective: This study aimed to compare complication rates between pylorus-preserving gastrectomy (PPG) and distal gastrectomy (DG) using Korean nationwide survey data and propensity score weighting (PSW). PPG preserves gastric function but may lead to more postoperative complications than DG.

Methods And Results: We analyzed 9424 gastric cancer patients who underwent either DG ( = 9183) or PPG ( = 241).

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  • The study aimed to compare the genetic profiles of poorly cohesive carcinoma (PCC) and well-differentiated tubular adenocarcinoma (WD) in gastric cancer, focusing on the role of the HIV-1 Tat Interactive Protein 2 (HTATIP2).
  • Using next-generation sequencing and immunohistochemistry on gastric cancer tissue and cell lines, researchers found that HTATIP2 and other genes showed reduced expression in PCC compared to WD.
  • The analysis revealed that higher levels of HTATIP2 were linked to better patient outcomes, including early-stage cancer and lower lymph node metastasis, suggesting it could serve as a promising prognostic marker and treatment target for gastric cancer.
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  • The study aimed to compare outcomes of laparoscopic primary repair (LPR) versus LPR combined with highly selective vagotomy (LPR-HSV) in patients with perforated duodenal ulcers.
  • A total of 184 patients were analyzed, revealing that LPR-HSV had a longer operation time but significantly shorter hospital stays and quicker recovery in starting soft diets compared to LPR.
  • The findings suggest that LPR-HSV could be a safe option for patients at high risk of ulcer recurrence, without significant differences in complication rates.
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Purpose: This study aimed to analyze the incidence and risk factors of complications following gastric cancer surgery in Korea and to compare the correlation between hospital complications based on the annual number of gastrectomies performed.

Materials And Methods: A retrospective analysis was conducted using data from 12,244 patients from 64 Korean institutions. Complications were classified using the Clavien-Dindo classification (CDC).

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  • Lipid emulsion is effective in treating systemic toxicity from local anesthetics and can also help with cardiovascular issues from other lipid-soluble drugs.
  • A case study involved a 47-year-old woman who suffered convulsions and loss of consciousness after receiving lidocaine for a procedure.
  • After being treated with midazolam and lipid emulsion, she improved her Glasgow Coma Scale score and fully recovered, highlighting the importance of early lipid emulsion treatment for lidocaine toxicity.
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  • * Initial symptoms included severe bronchospasms and desaturation, which failed to respond to usual treatments; her condition deteriorated, resulting in cardiac arrest even after administering medications like ephedrine.
  • * After receiving extracorporeal membrane oxygenation (ECMO) therapy, the patient regained some heart activity, successfully transitioning to a stable condition and was later discharged from the ICU without further complications.
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A 48-year-old female patient underwent a heart transplantation for acute fulminant myocarditis, following heterologous vaccination with the ChAdOx1 nCoV-19 and Pfizer-BioNTech COVID-19. She had no history of severe acute respiratory syndrome coronavirus-2 infection. She did not exhibit clinical signs or have laboratory findings of concomitant infection before or after vaccination.

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The aim of this study was to perform a clinicopathologic analysis of PHLPP1 expression in gastric cancer patients and analyze AKT activity with chemotherapy drug treatment in cancer subtypes. Surgically resected gastric cancer tissue specimens were obtained from 309 patients who underwent gastrectomy, and PHLPP1 expression was validated by tissue microarray analysis with immunohistochemistry. We assessed whether PHLPP1 selectively dephosphorylates Ser473 of AKT in an in-vitro study.

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  • The study examines how the volume of gastric remnants (GRVs) after gastrectomy affects patients' quality of life (QOL), specifically comparing those with small vs. large remnant volumes.
  • Researchers collected data from 78 gastric cancer patients who underwent distal gastrectomy, using questionnaires and CT scans to assess their QOL over time.
  • While dysphagia (difficulty swallowing) showed significant differences between the two groups after 6 months, overall QOL scores did not vary significantly at other time points, suggesting GRV volume has minimal impact on long-term functional outcomes.
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Introduction: There have been few studies about gene differences between patients with diffuse-type gastric cancer and those with intestinal-type gastric cancer. The aim of this study was to compare the transcriptomes of signet ring cell gastric cancer (worst prognosis in diffuse-type) and well-differentiated gastric cancer (best prognosis in intestinal-type); NUDC was identified, and its prognostic role was studied.

Materials And Methods: We performed next-generation sequencing with 5 well-differentiated gastric cancers and 3 of signet ring cell gastric cancer surgical samples.

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  • An abdominal binder may be an effective treatment option for patients experiencing cerebrospinal fluid (CSF) leakage at the coccygeal area.
  • This is particularly relevant for those suffering from post-dural puncture headaches.
  • The binder can be a suitable alternative when standard compressive dressings do not provide relief.
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Background: Prolotherapy is a proliferation therapy as an alternative medicine. A combination of dextrose solution and lidocaine is usually used in prolotherapy. The concentrations of dextrose and lidocaine used in the clinical field are very high (dextrose 10%-25%, lidocaine 0.

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Background: The aim of this study was to compare the 1 year incidence of Petersen's hernia between individuals who were treated with the jejunal mesentery fixing (Mefix) method and those with the closure of Petersen's space method.

Material And Methods: We retrospectively collected clinical data of patients who underwent gastrectomy for gastric cancers with the closure of Petersen's space defect ( = 49) and Mefix ( = 26). The Mefix method was performed by fixing the jejunal mesentery (jejunojejunostomy below 30 cm) to the transverse mesocolon using nonabsorbable barbed sutures.

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Background: The enhancer of rudimentary homolog (ERH) protein is implicated in transcriptional regulation, cell cycle progression, and malignancy. We previously conducted a proteomics analysis using gastric cancer (GC) tissues and identified ERH as a biomarker candidate. The aim of this study was to investigate whether ERH may be useful as a prognostic marker for GC.

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Diaphragmatic eventration, both congenital and acquired, is defined as abnormal elevation of the diaphragm. We report 2 cases of adult symptomatic diaphragmatic eventration successfully treated by laparoscopic diaphragmatic resection with an endostaple. These cases were observed for more than 1 year with no complications or recurrence after surgery.

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Peroxiredoxin IV (PRDX4) is a multifunctional protein that is involved in cell protection against oxidative injury, regulation of cell proliferation, modulation of intracellular signaling, and the pathogenesis of tumors. We previously conducted a proteomic analysis to investigate tumor-specific protein expression in gastric cancer. The aim of the present study was to investigate whether PRDX4 could be a marker of poor prognosis in patients with gastric cancer.

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This study aims to investigate the adaptation process of the alimentary tract after distal gastrectomy and understand the impact of remnant stomach volume (RSV) on diet recovery.One year after gastrectomy, although patients' oral intake had increased, the RSV was decreased and small bowel motility was enhanced. Patients with a larger RSV showed no additional benefits regarding nutritional outcomes.

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Background: Recently, researchers have tried to predict patient prognosis using biomarker expression in cancer patients. The aim of this study was to develop a nomogram predicting the 5-year recurrence-free probability (RFP) of gastric cancer patients using prognostic biomarker gene expression.

Methods: We enrolled 360 patients in the training data set to develop the predictive model and nomogram.

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Background: In our previous study, transumbilical endoscopic submucosal dissection (TU-ESD) was revealed to be feasible, but delayed gastric perforation was observed in 30% of ESD sites. In this study, we aimed to verify locations at which it is feasible to perform TU-ESD in the upper gastric body and to demonstrate the safety of TU-ESD in single-basin lymph node dissection (SBLND).

Methods: In vitro, TU-ESD was performed at three lesion sites (anterior wall, AW; posterior wall, PW; and lesser curvature, LC) in each porcine stomach using an EASIE-R tray (cases = 10).

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  • Diagnosing calf pain can be challenging due to its varied causes; careful history and physical exam are essential for accurate diagnosis.
  • Ultrasonography is recommended as the first-choice evaluation tool because it is accessible and cost-effective for identifying issues like fibromas.
  • A case study illustrates that a 35-year-old man's chronic calf pain was misdiagnosed for years until ultrasonography revealed a fibroma causing inflammation around the nerves, leading to successful treatment after surgery.
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