Publications by authors named "Mitsuru Obata"
[A Case of Ramucirumab-Related Small Intestinal Perforation in Gastric Cancer].
Gan To Kagaku Ryoho
December 2021
A 54-year-old man underwent laparoscopic distal gastrectomy with D2 lymph node dissection and ante-colic Roux-en-Y reconstruction for gastric cancer. The histopathological diagnosis was pT2N3aM0, pStage ⅢA, HER2 negative. After 8 courses of S-1 plus oxaliplatin as adjuvant chemotherapy, he was diagnosed as peritoneal dissemination and treated with ramucirumab(RAM)plus paclitaxel(PTX).
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- A 77-year-old man with advanced ascending colon cancer was diagnosed with stage IV and treated with mFOLFOX6 plus Bmab chemotherapy.
- On the second day of treatment, he experienced consciousness disturbances, leading to the diagnosis of a convulsive seizure, but his condition improved with intravenous fluids.
- Following this, he developed hyperammonemic encephalopathy during subsequent treatments but responded well to BCAA infusion, allowing for continued chemotherapy with added medications to manage ammonia levels.