Cartilage assessment using preoperative planning MRI for femoral component rotational alignment.

Background: Surgical planning of posterior referencing total knee arthroplasty (TKA) using computed tomography (CT) might lead to over-rotation of the femoral component because CT could not detect cartilage thickness of the posterior femoral condyle. The purpose of this study was to examine the rotational alignment difference of the femoral component between magnetic resonance imaging (MRI) and CT.

Methods: For elderly varus osteoarthritic patients, 66 varus osteoarthritic knee patients that underwent primary TKA were selected.

In vitro cartilage formation using TGF-beta-immobilized magnetic beads and mesenchymal stem cell-magnetic bead complexes under magnetic field conditions.

We evaluated the efficacy of transforming growth factor (TGF)-beta-immobilized magnetic beads for chondrogenesis in vitro using a mesenchymal stem cell (MSC) delivery system and an external magnetic force (EMF). MSCs isolated from the bone marrow of Sprague Dawley rats were mixed with carboxyl group-combined magnetic beads (Ferri Sphere 100C) coated with anti-rat CD44 mouse monoclonal antibodies. TGF-beta3 (10 and 1 ng/mL) was attached magnetically to such other Ferri Sphere 100C beads via an amide bond formed between a primary amino group on the TGF-beta3 and the carboxyl groups on the surface of the beads.

Functional and radiographic outcome of stable juvenile osteochondritis dissecans of the knee treated with retroarticular drilling without bone grafting.

Purpose: The purpose of this study was to evaluate the functional and radiographic outcome of retroarticular drilling for patients with juvenile osteochondritis dissecans after 6 months of unsuccessful nonoperative treatment.

Methods: A total of 20 osteochondritis dissecans lesions in 12 skeletally immature patients were treated with retroarticular drilling without bone grafting. There were 10 boys and 2 girls with a mean age of 12.

Articular cartilage injury of the posterior lateral tibial plateau associated with acute anterior cruciate ligament injury.

Thirty-nine knees in 39 patients with recent anterior cruciate ligament (ACL) rupture (age 14-55 years; with a mean age of 22.8 years) were selected from our cases of ACL reconstruction from July 2005 to June 2006, to take part in a study on articular cartilage injury of the posterior lateral tibial plateau associated with acute ACL injury and on the correlation between bone bruises depicted on MRI and cartilage injury of the posterior lateral tibial plateau detected at arthroscopic ACL reconstruction. Using preoperative MRI, we evaluated whether there were bone bruises or not in the lateral compartment of the knee and divided them accordingly into two groups: the bone bruise positive group and the negative group.