Higher Red Blood Cell Distribution Width Is an Adverse Prognostic Factor in Chronic-phase Chronic Myeloid Leukemia Patients Treated with Tyrosine Kinase Inhibitors.

The significance of red blood cell distribution width (RDW) was evaluated in patients with chronic myeloid leukemia (CML) in the chronic phase (CP). Eighty-four patients with newly-diagnosed CML-CP treated with any tyrosine kinase inhibitor (TKI) were analyzed. Patients were divided into two groups: a low-RDW group (RDW values ≤15%, n=31) and a high-RDW group (RDW values >15%, n=53).

The European Treatment and Outcome Study score is associated with clinical outcomes and treatment response following European LeukemiaNet 2013 recommendations in chronic-phase chronic myeloid leukemia.

The introduction of tyrosine kinase inhibitors has dramatically improved outcomes for many patients with chronic myeloid leukemia (CML), but some cases are resistant to this treatment. To compare the prognostic performance of Sokal, Hasford, and European Treatment and Outcome Study (EUTOS) scores, patient outcomes and treatment responses were investigated following the European LeukemiaNet (ELN) 2013 recommendations. Seventy-three patients with newly diagnosed chronic-phase CML (CML-CP) treated with any tyrosine kinase inhibitor as initial therapy were analyzed.

Rapid on-site air sampling with a needle extraction device for evaluating the indoor air environment in school facilities.

A rapid on-site air sampling technique was developed with a miniaturized needle-type sample preparation device for a systematic evaluation of the indoor air environments in school facilities. With the in-needle extraction device packed with a polymer particle of divinylbenzene and activated carbon particles, various types of volatile organic compounds (VOCs) were successfully extracted. For evaluating the indoor air qualities in school facilities, air samples in renovated rooms using organic solvent as a thinner of the paint were analyzed along with measurements of several VOCs in indoor air samples taken in newly built primary schools mainly using low-VOCs materials.

High-temperature separations on a polymer-coated fibrous stationary phase in microcolumn liquid chromatography.

Novel polymer-coated fiber-packed microcolumns in liquid chromatography (LC) have been developed. Typical polymeric materials, such as polydimethylsiloxane and polyethyleneglycol, which are conventional stationary phases of capillary columns in gas chromatography (GC), have been employed as coating materials onto the surface of fine filaments. Packed longitudinally with a bundle of polymer-coated filaments into a stainless-steel capillary of 0.

Rapid temperature-programmed separation and retention prediction on a novel packed-capillary column in gas chromatography.

Novel packed-capillary columns for gas chromatography were developed with a thin-wall stainless-steel capillary of 1.0 mm i.d.

Cytogenetic abnormalities in hepatoblastoma: report of two new cases and review of the literature suggesting imbalance of chromosomal regions on chromosomes 1, 4, and 12.

Two cases of hepatoblastoma with unique karyotypic changes are described. One case was that of a 2-year-old boy with an unbalanced chromosomal translocation involving 4q35 as the sole chromosomal abnormality. The clonal karyotype of this tumor was 46,XY,add(4)(q35)[3]/46,XY[9].

[Human herpesvirus-8 negative primary effusion lymphoma with complete clinical remission after removal of ascites].

A 58-year-old HIV-negative woman was admitted to our hospital with abdominal distension. She had a 5-year history of hypothyroidism and a 4-year history of diabetes mellitus. Physical examination revealed ascites.