Publications by authors named "Mitsuru Aoyagi"
Article Synopsis
- The study explored how tetrodotoxin (TTX) is excreted through a specific cell line, showing a linear increase in TTX transport at normal temperature (37 °C) versus a significant decrease at low temperature (4 °C).
- Transport of TTX involves a combination of transcellular processes and carrier-mediated mechanisms, influenced by various transport inhibitors.
- The findings highlight that TTX primarily relies on organic cation and carnitine transporters, with lesser involvement from organic anion transporters and multidrug resistance proteins.
Both hexachlorobenzene and hexabromobenzene were successfully hydrodehalogenated to the monohalogenated derivative and ultimately to benzene (which was subsequently reduced to cyclohexane) using a mixture of metallic Ca, ethanol, and Rh/C, by simple stirring in diethyl ether, at room or mild temperature (60 °C). Various experiments were performed in order to assess the role of the solvent and Rh/C catalyst, as well as for elucidating the reaction pathway.
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