Organogermanium compound, Ge-132, forms complexes with adrenaline, ATP and other physiological cis-diol compounds.

Background: In mammals, adrenaline and ATP are life-essential vicinal diol and cis-diol functional groups. Here, we show that interactions between a safe organogermanium compound and these cis-diol compounds have the potential to regulate physiological functions. In addition, we represent a possible new druggable target for controlling the action of cis-diol compounds.