Publications by authors named "Mitsumasa Koizumi"
Article Synopsis
- Resistance to potassium tellurite (PT) is crucial for isolating Shiga toxin-producing E. coli (STEC) O157:H7, and a study identified an O157:H7 strain that resists PT despite lacking the common resistance gene cluster.
- Whole-genome sequencing revealed a nonsynonymous mutation in a different PT resistance gene, which was found to enhance PT resistance by increasing the expression of this gene through a change in its internal promoter.
- This research indicates that even strains without the typical resistance genes can achieve PT resistance due to single mutations, highlighting the adaptability of STEC in various environments.
An outbreak of enterohemorrhagic Escherichia coli (EHEC) O157:H7 infection occurred in October 2016 in Kanagawa, Japan. A total of 61 patients and 17 asymptomatic cases of EHEC O157:H7 infection were confirmed by laboratory testing. Among them, 24 patients were hospitalized and 4 developed hemolytic-uremic syndrome.
View Article and Find Full Text PDF