Publications by authors named "Mitsuki Tezuka"
Article Synopsis
- FOXO3 is essential for maintaining cochlear hair cells, with growth factors like TGF-β playing a key role in their regeneration.
- Treatment with TGF-β receptor inhibitor EW-7197 enhances FOXO3 expression and promotes cilia-like structure growth while inhibiting cell migration and increasing metabolic activity.
- The study suggests that FOXO3/TGF-β signaling is crucial in the differentiation of cochlear hair cells, indicating potential therapeutic avenues for hearing loss prevention.
Introduction: Leptin, a 16 kDa circulating anti-obesity hormone, exhibits many physiological properties. Recently, leptin was isolated from saliva; however, its function in the oral cavity is still unclear. In this study, we investigated the physiological role of leptin in the oral cavity by focusing on its effect on wound healing in the oral mucosa.
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