Publications by authors named "Mitsuhiro Kimura"

Background: Evaluating the correlation between degenerative meniscus tears and medial meniscus extrusion is necessary to determine the appropriate treatment plan for early-stage knee osteoarthritis. This study evaluated the relationship between degenerative meniscal tears and medial meniscus extrusion in early-stage knee osteoarthritis by using ultrasonography.

Methods: A total of 132 knees from 123 patients with early-stage knee osteoarthritis were evaluated retrospectively.

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Background: Foot rock-paper-scissors and towel-gathering exercises are widely used for isometric strengthening of intrinsic foot muscles. An initial trial demonstrated that foot rock-paper-scissors and towel-gathering exercises affected skeletal muscles associated with the medial longitudinal arch and toe pressure force, respectively. However, no quantitative reports of interosseous muscle activity after continuous training exist.

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Background Psychological state has been reported as one of the factors strongly related to a return to sports after anterior cruciate ligament (ACL) reconstruction. However, its relationship with the emotional state remains unclear. The aim of this study was to investigate whether patients who have undergone ACL reconstruction and have a higher preoperative psychological competitive ability have a better emotional status preoperatively and six months postoperatively.

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Article Synopsis
  • This study looked at how blood flow signals (BFSs) in the bone can help find bone problems called bone marrow lesions (BMLs) in people with early knee arthritis.
  • They checked 77 patients who had knee pain and used two types of tests: ultrasound (US) for BFSs and MRI for BMLs.
  • The results showed a strong link between BFSs and BMLs, meaning BFSs can be a good way to check for bone issues in the knee.
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Intracellular delivery of biomolecules is a prerequisite for genetic techniques such as recombinant engineering and genome editing. Realizing the full potential of this technology requires the development of safe and effective methods for delivering protein tools into cells. In this study, we demonstrated the spontaneous internalization of exogenous proteins into intact cells and root tissue of whole plants of Arabidopsis thaliana.

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The aim of this study was to identify anatomical and clinical factors associated with limb-based patency (LBP) loss, major adverse limb events (MALEs), and poor amputation-free survival (AFS) after an infrapopliteal arterial bypass (IAB) surgery according to the Global Limb Anatomic Staging System. A retrospective analysis of patients undergoing IAB surgery between January 2010 and December 2021 at a single institution was performed. Two-year AFS, freedom from LBP loss, and freedom from MALEs were assessed using the Kaplan-Meier method.

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The purpose of the study was to investigate the relationship between diffusion tensor imaging (DTI) and the clinical classification of cubital tunnel syndrome (CuTS). Ten patients with CuTS (7 men and 3 women; mean age: 52.7 years) and 5 patients without ulnar neuropathy (2 men and 3 women; mean age: 38.

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Objective: This prospective study aimed to investigate the relationship between preoperative psychological competitive ability and preoperative and 6 months postoperative subjective knee function in patients undergoing anterior cruciate ligament (ACL) reconstruction.

Methods: Eighty-four patients who underwent ACL reconstruction and had a Tegner Activity Scale score of 6 or more were included in this study. Preoperatively, all patients were administered the Diagnostic Inventory of Psychological Competitive Ability for Athletes (DIPCA.

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Purpose: We aimed to explore the applicability and validity of ultrasonography for diagnosing chronic posterior cruciate ligament (PCL) injuries.

Methods: PCL thickness was measured at 2 cm proximal to the tibia insertion site. Using the same ultrasonography image, the angle tangent to the PCL from the tibia insertion site was also measured.

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Purpose: To compare the biomechanical strength of different fixation configurations using a suspensory button in a soft-tissue quadriceps tendon graft for Anterior Cruciate Ligament (ACL) reconstruction.

Methods: Thirty fresh-frozen bovine Achilles tendons (10 mm wide, 50 mm long, and 4 mm thick) were used in this study. Tendons were assigned to three groups (n = 10 per group) with different suture configurations using adjustable loops with a suspensory button: group A, with the threads of an adjustable loop fixed by crossing at the tip of the loop and the entire loop; group B, continuous loops with hanging buttons were directly sutured to the tendon with eight simple sutures; group C, fixation was performed using the speed whip ripstop technique.

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Article Synopsis
  • The study aimed to analyze how growth affects the ultrastructural properties of the quadriceps tendon (QT) across different age groups.
  • It categorized 18 patients into three groups: immature (ages ~11.5), young (ages <20), and adult (ages >20) to examine collagen fibril diameters using electron microscopy.
  • Results indicated that collagen fibril diameter increased with age, showing significant differences between immature/young groups and adults, suggesting important implications for tendon graft selection in medical applications.
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Objective: A centrifugation-assisted peptide-mediated gene transfer (CAPT) method was recently developed as an efficient system for gene delivery into plant cells. However, the gene transfer efficiency of CAPT into plant cells was not entirely satisfactory for detecting transient expression of a transgene driven into mitochondria. Here, we report a new gene delivery system using a method called particle bombardment-assisted peptide-mediated gene transfer (PBPT).

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[Purpose] This study aimed to identify the relationship between the early postoperative perceived leg length discrepancy after unilateral total hip arthroplasty and the progression of osteoarthritis in the contralateral hip. [Participants and Methods] This was a retrospective cohort study of 65 patients who underwent primary unilateral total hip arthroplasty for bilateral hip osteoarthritis. The minimum joint space width of the contralateral hip was measured preoperatively.

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In sumo wrestling, a traditional sport in Japan, many wrestlers suffer from injuries through bouts. In 2019, an average of 5.2 out of 42 wrestlers in the top division of professional sumo wrestling were absent in each grand sumo tournament due to injury.

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Purpose: The rectus femoris has three myotendinous or myoaponeurosis junctions and causes three types of muscle strain anatomically. We aimed to investigate the anatomical injury site of the rectus femoris muscle strain in professional soccer players as well as the characteristic findings on magnetic resonance imaging (MRI) and to evaluate its relationship with the time taken to return to play at competition levels.

Methods: Thirteen Japanese professional soccer players who sustained injuries to the rectus femoris were included in this study.

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Article Synopsis
  • The study assessed the risk of "ligamentization" in patients who underwent ACL reconstruction using ultrashort echo time (UTE)-T2* imaging.
  • Fifty-nine patients were evaluated six months post-surgery, with UTE T2* values calculated from different regions of their reconstructed ACL.
  • Results showed no significant differences in clinical outcomes between groups classified by UTE T2* values, but higher graft tension was identified as a risk factor for increased UTE T2* values.
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Purpose: The purpose of this study was to evaluate the mechanical properties, such as the tensile strength and load distribution function, of the meniscus tissue regenerated using adipose-derived stem cell (ADSC) sheets in a rabbit meniscal defect model.

Methods: ADSC sheets were prepared from adipose tissue of rabbits. The anterior half of the medial meniscus was removed from both knees.

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Background: The purpose of this study was to prospectively observe the trends of ultrashort echo time (UTE)-T2* values for the intraarticular and intraosseous regions of reconstructed anterior cruciate ligaments from 6 to 12 months after anterior cruciate ligament reconstruction by using UTE-T2* mapping, and to investigate the changes and differences over time in each region.

Methods: Ten patients underwent UTE-T2* mapping of the operated knee at 6, 9, and 12 months after anterior cruciate ligament reconstruction. The UTE-T2* values of intraarticular and intraosseous regions of reconstructed anterior cruciate ligaments at 6, 9, and 12 months postoperatively were statistically compared.

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Background: In this study, we investigated newly developed ultrasound (US)-guided medial collateral ligament (MCL) bursa injection as a conservative therapy for symptomatic degenerative medial meniscal (MM) tears. We aimed to describe the anatomical target and precise technique of this injection, confirm its accuracy using fresh cadaveric knees, and then evaluate preliminary clinical outcomes.

Methods: Anatomical studies were performed on three fresh cadavers.

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Genome editing in plants employing recombinant DNA often results in the incorporation of foreign DNA into the host genome. The direct delivery of genome-editing proteins into plant tissues is desired to prevent undesirable genetic alterations. However, in most currently available methods, the point of entry of the genome-editing proteins cannot be controlled and time-consuming processes are required to select the successfully transferred samples.

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Purpose: To examine the optimal number and combination of -values in intravoxel incoherent motion (IVIM) diffusionweighted imaging (DWI) of the major salivary glands.

Material And Methods: IVIM-DWI was performed on 10 healthy volunteers using 13 -values (low -values: 0-100 s/mm; high -values: 200-1000 s/mm). The IVIM parameters and apparent diffusion coefficient of the bilateral major salivary glands were calculated using 13 -values and were considered the standard values.

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This study was conducted to investigate the incidence of lumbar degeneration findings and low back pain (LBP) in children and adolescent weightlifters using magnetic resonance imaging (MRI) and medical questionnaires over a 5-year period. Moreover, we aimed to reveal the temporal changes in the lumbar vertebrae caused by long-term weightlifting training during the growth period. Twelve children and adolescent weightlifters who participated in weightlifting for >2 years (six boys, six girls, 11.

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Osgood-Schlatter disease commonly affects physically active adolescents. It is a common cause of anterior knee pain and inflammation in this population. Its symptoms typically subside with conservative therapy.

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Posterior cruciate ligament (PCL) tibial avulsion fractures in children are extremely rare. Due to the rarity of these injuries, careful attention to the specific physical examination and imaging findings is necessary for a proper diagnosis. PCL avulsion fractures can be missed on plain radiography in skeletally immature patients.

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