Publications by authors named "Mitsuhiko Eto"
Article Synopsis
- Systemic and localized scleroderma are conditions marked by excessive collagen buildup and skin fibrosis, but their specific mechanisms remain poorly understood.
- The study focused on microRNAs (miRNAs) and their potential role in this fibrotic process, using various analysis techniques to examine miRNA expression in affected tissues.
- The key finding was that let-7a is significantly downregulated in patients with scleroderma, and increasing its levels shows promise in reducing skin fibrosis in animal models, suggesting a potential new avenue for treatment.
