Publications by authors named "Mitra Kar"

Ralstonia species are recently emerging as pathogens of human importance. This study was performed to assess the distribution of Ralstonia species among bacteremia patients and the clinical and demographical factors of these patients. This retrospective observational study was performed in the Microbiology Department of a tertiary care center in North India from April 2022 to April 2024.

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Article Synopsis
  • Burkholderia spp., which are opportunistic pathogens, primarily infect individuals with compromised immune systems; this study examined how these bacteria cause blood infections (bacteremia) in patients from a northern Indian university hospital over one year.
  • Among 300 patients, the average age was about 34 years, with a majority being male; underlying malignancies were the most common diagnosis, and all patients had catheters, with Burkholderia cenocepacia being the most frequently isolated type.
  • Factors such as kidney disease, hypertension, type 2 diabetes, and respiratory disease increased the risk of death from these infections, while patients with malignancies often had better outcomes if the bacteria were treatable with antibiotics.
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Introduction: Intestinal parasitic infections pose a substantial threat to public health and are a huge burden to the economic development of a developing country. We aimed to identify the spectrum of intestinal parasitic infections with an emphasis on demographic and clinical characteristics observed among immunocompromised and immunocompetent patients.

Materials And Methods: This observational study was performed in the Parasitology section of the Department of Microbiology from January 2022 to July 2022.

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Article Synopsis
  • * Conducted in Northern India over nearly four years, the study analyzed 72 TBI patients, who predominantly suffered from ventilator-associated pneumonia (VAP) and bloodstream infections, revealing a significant presence of multidrug-resistant bacteria.
  • * Key risk factors for infections included longer hospital stays, ICU admissions, and existing health issues like diabetes and chronic kidney disease, indicating a need for stricter infection control measures to protect TBI patients.
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Introduction: species are emerging bacteria capable of causing nosocomial infections in immunocompromised patients or patients with indwelling medical devices.

Hypothesis/ Gap Statement: Information about the incidence of bacteremia from worldwide literature is limited.

Aim: We aimed to recognize the clinical characteristics, frequency of distribution of different species isolates, and their antimicrobial susceptibility profile from bloodstream infections.

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Background: Meningitis can be attributed to bacterial, fungal, or viral agents. In this study, we demonstrate the common bacterial agents causing meningitis along with their antibiotics susceptibility pattern in patients of all age groups.

Material And Methods: This retrospective, observational study was carried out in the Department of Microbiology with cerebrospinal fluid (CSF) samples collected from November 2019 to May 2022.

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Introduction: Bile is deemed a sterile fluid, with the presence of clinical conditions like cholelithiasis, cholecystitis, previous biliary interventions, biliary strictures, and so on, leading to bile stasis, and increases the chances of bacteriobilia. In this study, we recognize the bacterial spectrum of microorganisms isolated from bile samples, diagnostic parameters, and antibiotic sensitivity patterns.

Methods: A retrospective observational study was carried out by compiling data from the hospital information system of a tertiary care center from 2021 to 2022 to evaluate biliary infections in patients who underwent surgical procedures related to the biliary tract and associated organs.

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Introduction: is a Gram-negative, motile, obligate aerobic and non-fermentative bacterium. It is an emerging pathogen in the hospital environment as it is frequently found in various solutions.

Hypothesis/gap Statement: Information about the incidence and risk factors of bacteremia from India is limited.

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 Isepamicin is a 1-N-S-a-hydroxy-b-aminopropionyl derivative of gentamicin B and the spectrum of pathogenic microorganisms covered by it and its effectiveness is similar to that of amikacin except the action of aminoglycoside inhibitor enzymes is ineffectual on it.  We performed a prospective study in the Bacteriology section of the Department of Microbiology at a 1,600-bedded hospital in Northern India from Jan 2022 to March 2022. Isepamicin was tested for susceptibility against gram-negative bacteria, identified by routine biochemicals and matrix-assisted-desorption/ionization -time of flight-mass spectrometry (MALDI-TOF-MS) assay.

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Background: Blockage of the biliary tract is commonly caused by malignant tumors leading to deranged liver function, responsible for poor prognosis and a high rate of leading to mortality.

Material And Methods: We collected retrospective data from the hospital information system and laboratory registers in our department from 2021 to 2022 to evaluate biliary infections in patients with hepato-pancreatico-biliary and associated intraabdominal malignancies.

Result: A total of 118 (118/234, 50.

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Introduction: Patients with coronavirus disease-2019 (COVID-19) are prone to develop respiratory bacterial infections irrespective of their need for mechanical ventilatory support.

Hypothesis/gap Statement: Information about the incidence of concomitant respiratory bacterial infections in COVID- 19 patients from India is limited.

Aim: This study aimed to determine the incidence of concomitant respiratory bacterial pathogens and their drug resistance in these patients.

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Context: Knowledge of epidemiology of bacterial isolates and their anti-biograms in hospital settings is necessary for prompt empirical anti-microbial therapy of neonatal sepsis.

Aims: To study risk factors, bacteriological profiles, and anti-biograms of blood culture isolates of both early and late onset neonatal sepsis.

Settings And Design: It is a prospective observational study conducted from January 2020 till July 2021 at our tertiary care center.

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Background: Cerebrospinal infections are the cause of poor prognosis among post-neurosurgery patients owing to delay in improvement of neurological functions, leading to increased length of hospital stay, proceeding to disability or death.

Methods And Materials: This retrospective observational study was performed at a tertiary care center in Northern India, where all patients with bacterial cerebrospinal infections from July 2019 to July 2022 were evaluated for post-neurosurgery cerebrospinal shunt infections, and all demographic data and risk factors were extracted from the hospital information system (HIS).

Results: The study includes 150 (150/1986, 7.

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Introduction: Diagnosis of tuberculous peritonitis (TBP) requires a high index of suspicion.

Hypothesis /gap Statement: Information about the diagnostic features of TBP among patients with end-stage renal failure (ESRF) from India is limited.

Aim: To assess the utility of the Gene Xpert MTB/RIF assay in the diagnosis of TBP in patients with end-stage renal failure (ESRF), compared with those without ESRF.

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Introduction: Infections associated with catheter in the upper urinary tract (CUUT), which include the double-J stent and the percutaneous nephrostomy (PCN) tube, get particularly infected in patients with specific risk factors for developing an infection.

Methods: A retrospective observational study was carried out by compiling data from the hospital information system of a tertiary care center from 2019 to 2021 to evaluate infections in patients with catheter in the upper urinary tract.

Result: A total of 200 pus samples of double-J stent (96 pus samples) and PCN tube (104 pus samples) were included in our study.

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