Publications by authors named "Mithra Maneyapanda"

Background: Sleep disturbance is a common sequela after traumatic brain injury (TBI). Many of the impairments following TBI may be exacerbated by impaired sleep-wake cycle regulation.

Objectives: To investigate the relationship between total sleep time (TST), measured by wrist actigraphy and observational sleep logs, and neurobehavioral impairments during inpatient rehabilitation after TBI.

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Background: Intrathecal baclofen (ITB) often is used to treat severe spasticity of cerebral origin. Although literature exists regarding the efficacy of ITB, there has been minimal investigation related to dosing in the adult-acquired brain injury population, particularly at long-term duration.

Objective: To investigate long-term dosing of ITB in adult patients with spasticity of cerebral origin due traumatic brain injury (TBI), stroke, and hypoxic-ischemic encephalopathy (HIE).

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Unlabelled: Baclofen is a commonly used medication to treat spasticity in neurologic disorders. In the traumatic brain injury (TBI) population, the intrathecal administration of baclofen is often preferred over oral administration due to cognitive side effects. Here we report on a case of a psychotic episode following an increase in intrathecal baclofen in a young man with a history of a TBI.

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Article Synopsis
  • Intrathecal baclofen (ITB) therapy is used to treat spasticity from neurological issues, but pump refill can be difficult due to factors like excess fat and scar tissue.
  • Multiple attempts to refill can lead to pain, infection risks, and complications such as baclofen withdrawal syndrome.
  • The article presents successful ITB refills using ultrasound guidance, highlighting its potential to enhance safety and effectiveness in challenging cases.
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