A Qualitative Study on the Burden of Nonadherence to Antiretroviral Therapy Among People Living With HIV/AIDS in Jharkhand, India.

Background: Adherence to antiretroviral therapy (ART) is the most important factor in the management of human immunodeficiency virus (HIV). This study examines the level of nonadherence to ART and the predictors of interventions to improve ART adherence in Jharkhand, a state with a predominance of tribes.

Methods: The present study was conducted at the ART center, Rajendra Institute of Medical Sciences (RIMS), Ranchi, Jharkhand.

A Comparative Study on Antiretroviral Therapy (ART) Adherence Among the Tribal and Non-tribal Populations Living With HIV/AIDS in Ranchi, India.

Background: Acquired immunodeficiency syndrome (AIDS) is one of the most serious public health exigencies across the globe. However, equally brawny is the global commitment to halt new HIV infections from occurring and ensure that everyone with the disease has access to HIV treatment.

Materials And Methods: A cross-sectional analytical study was carried out at an antiretroviral therapy (ART) center in Ranchi, Jharkhand, India, in 2023.

An Analysis of Antibody Response to COVID-19 Vaccination Among Medicos in a Predominantly Tribal State in India: A Comparative Study.

Introduction Global health is still being impacted by the coronavirus disease 2019 (COVID-19) pandemic. Objectives We evaluated the antibody response in this study in individuals who received two doses of the COVID-19 vaccination, both with and without a history of SARS-CoV-2 infection. Methodology It was a hospital-based cross-sectional study conducted among healthcare personnel at a tertiary institution of a predominantly tribal state in India.

Evaluating the efficacy of artificial intelligence tools for the automation of systematic reviews in cancer research: A systematic review.

To evaluate the performance accuracy and workload savings of artificial intelligence (AI)-based automation tools in comparison with human reviewers in medical literature screening for systematic reviews (SR) of primary studies in cancer research in order to gain insights on improving the efficiency of producing SRs. Medline, Embase, the Cochrane Library, and PROSPERO databases were searched from inception to November 30, 2022. Then, forward and backward literature searches were completed, and the experts in this field including the authors of the articles included were contacted for a thorough grey literature search.

Medical and social implications of alcohol use among adult women in a rural area of Ranchi, Jharkhand: A cross-sectional study.

Introduction: The harmful use of alcohol is increasing at a huge pace leading to the occurrence of multiple diseases and has become a leading risk factor for global burden of diseases.

Aims And Objectives: The aim of this study is to assess the health profile of adult women and to find out the medical and social effects of alcohol consumption.

Methodology: A cross-sectional study was conducted in the rural field practice area, Ormanjhi of RIMS, Ranchi, for a duration of 27 months (September 2016 to November 2018) among 336 women by multistage random sampling.

The Expression of the RUVBL1 Component of the R2TP Complex Correlates with Poor Prognosis in DLBCL.

Introduction: Diffuse large B-cell lymphoma (DLBCL) is the most prevalent subtype of non-Hodgkin's lymphoma (NHL) accounting for 30% of adult NHL worldwide and 50% in developing countries like India. DNA damage and Myc-induced transformation are well-known contributing factors towards development of DLBCL. A recently identified HSP90 co-chaperone complex R2TP has been shown to contribute towards DNA damage and Myc-induced transformation.

Effect of milk supplementation on the status of micronutrients among rural school children aged 5-19 years in a tribal predominating district of India.

Background: In the tribal state of Jharkhand, there have been very few studies on micronutrient deficiency and how it is addressed among school children. This study was conceived and undertaken to assess the effect of milk supplementation on the micronutrient status of school children.

Design: A comparative observational study was conducted among school children of a tribal district in India during 2017-2018.

Bilateral hip arthroscopy for treating femoroacetabular impingement: a systematic review.

Purpose: Femoroacetabular impingement (FAI) is a hip disorder which can often present bilaterally. The purpose of this systematic review was to explore the current practices for bilateral hip arthroscopy in treating FAI as they relate to outcomes and complications.

Methods: This review has been conducted according to the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA).

Effects of preoperative walking ability and patient's surgical education on quality of life and functional outcomes after total knee arthroplasty.

Objective: Prospectively analyze the effect of preoperative walking status and the patient's surgical education on functional outcomes and the three dimensions of quality of life (QoL) (pain, physical function, and mental health) after elective total knee arthroplasty (TKA).

Methods: A comparative analysis on the QoL and functional outcomes in patients who underwent total knee arthroplasty between January 2014 and June 2015. To compare effects of the patient's walking status and knowledge of the surgical procedure on QoL and functional outcomes following TKA by means of SF-36 questionnaire, CES D10, VAS, KSS, KSFS, WOMAC, as well as Friedmann and Wyman scores, 10MWT, and 30-second timed chair test, assessed before the operation and one, three, and six months after the operation.

Biokinetic model-based multi-objective optimization of Dunaliella tertiolecta cultivation using elitist non-dominated sorting genetic algorithm with inheritance.

Algal model based multi-objective optimization using elitist non-dominated sorting genetic algorithm with inheritance was carried out for batch cultivation of Dunaliella tertiolecta using NPK-fertilizer. Optimization problems involving two- and three-objective functions were solved simultaneously. The objective functions are: maximization of algae-biomass and lipid productivity with minimization of cultivation time and cost.

Effect of change in sequence of administration of DTwP and Hepatitis B vaccines on perception of pain in infants: A randomized control trial.

Objective: This study was designed with objective to study pain response of infants to change in sequence of administration of Hepatitis B and DTwP vaccines.

Methods: This was a randomized parallel control trial. The study was carried out in the immunization clinic of the Department of Pediatrics, LLRM Medical College, Meerut.

Effects of Osteoarthritis on Quality of life in Elderly Population of Bhubaneswar, India: A Prospective Multicenter Screening and Therapeutic Study of 2854 Patients.

Introduction: Osteoarthritis (OA) is the most common age-related joint disease affecting >80% people beyond 55 years of age. It is a leading cause of elderly visit to outpatient departments and accounts for almost half of all nonsteroidal anti-inflammatory drug prescriptions. The burden and impact of knee OA in Indian population and extent of public health services usage by people with OA are not known.

Validity of non-invasive point-of-care hemoglobin estimation in healthy and sick children-a method comparison study.

Unlabelled: This study was conducted at a tertiary care center in northern India to evaluate the validity of non-invasive transcutaneous hemoglobin estimation in healthy and sick children in comparison to hemoglobin estimation by traditional lab method. A method comparison study was conducted including 150 subjects. Enrolled patients included 80 neonates with average age of 3.

Numerical study on influence of cross flow on rewetting of AHWR fuel bundle.

Numerical study on AHWR fuel bundle has been carried out to assess influence of circumferential and cross flow rewetting on the conduction heat transfer. The AHWR fuel bundle quenching under accident condition is designed primarily with radial jets at several axial locations. A 3D (r, θ, z) transient conduction fuel pin model has been developed to carry out the study with a finite difference method (FDM) technique with alternating direction implicit (ADI) scheme.

Genotoxicity of crotonaldehyde in the bone marrow and germ cells of laboratory mice.

Genotoxicity of crotonaldehyde was evaluated by employing bone marrow and spermatocyte chromosomal aberration and dominant lethal mutation assays in Swiss albino mice. For bone marrow chromosomal aberration assay, animals were treated with 0.2ml olive oil containing 8, 16 and 32microl kg b.

In vivo evaluation of induction of abnormal sperm morphology in mice by an unsaturated aldehyde crotonaldehyde.

Crotonaldehyde, a highly reactive unsaturated aldehyde is used for the manufacture of sorbic acid, synthesis of butyl alcohol, butylaldehyde, quinaldine, thiophenes, pyridines, dyes, pesticides, pharmaceuticals, rubber antioxidants, chemical warfare agents, etc. and also occurs naturally in meat, fish, in many fruits and vegetables, bread, cheese, milk, beer, wine and liquors. Human exposure to crotonaldehyde occurs from both man-made and natural sources.

Development of a hybrid delta-endotoxin and its expression in tobacco and cotton for control of a polyphagous pest Spodoptera litura.

A hybrid delta-endotoxin protein was designed against a polyphagous lepidopteran insect pest Spodoptera litura, which is tolerant to most of the known delta-endotoxins. The hybrid delta-endotoxin was created by replacing amino acid residues 530-587 in a poorly active natural Cry1Ea protein, with a highly homologous 70 amino acid region of Cry1Ca in domain III. The truncated delta-endotoxins Cry1Ea, Cry1Ca and the hybrid protein Cry1EC accumulated in Escherichia coli to form inclusion bodies.

Genotoxicity of lomefloxacin--an antibacterial drug in somatic and germ cells of Swiss albino mice in vivo.

The in vivo genotoxicity of lomefloxacin, a diflourinated antibacterial drug, was evaluated by employing mouse in vivo chromosomal aberration test in bone marrow cells and dominant lethal mutation assay in germ cells. Statistically significant reduction in mitotic index, increase in chromosomal aberrations (CAs)/cell and percent abnormal metaphase was observed only at the highest dose (160 mg/kg b.w.