Publications by authors named "Mitesh Karn"

This report presents a 14-year-old male with seizures and facial port-wine stains, who upon further evaluation was found to have SWS. Early diagnosis and consistent treatment of Sturge-Weber syndrome in children are essential to prevent seizures and improve quality of life. Anti-seizure medications play a crucial role in preventing and controlling seizures.

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. This article details the development and use of a low-cost, custom RMST device for a patient with long COVID who had received positive airway flow support during ICU treatment. By sharing our successful management of respiratory muscle weakness in a severe COVID-19 patient, we aim to contribute to the broader conversation around effective long COVID management.

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Background: Information regarding seropositivity and vaccine efficacy among medical students is scarce. This study aims to detect the status of SARS-CoV-2 neutralizing antibodies among the Sinopharm's Vero Cell (BBIBP-CorV) vaccinated medical students.

Materials And Methods: A prospective, cross-sectional study was carried out among medical students of Gandaki Medical College Teaching Hospital, Pokhara, Nepal from March through August 2022.

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Retroperitoneal spindle cell neoplasms are diagnostically challenging. Malignant peripheral nerve sheath tumours (MPNSTs) can sometimes present as sporadic primary retroperitoneal tumours. MPNSTs are usually high-grade and highly aggressive tumours and are associated with a poor prognosis.

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Article Synopsis
  • Neuro-ophthalmic issues, which can lead to permanent visual problems, are common in patients with traumatic head injuries but often overlooked, prompting the study to investigate their occurrence, neurological status, and neuroimaging results.
  • A total of 377 patients with head injuries were examined; most were males (71.9%), with road traffic accidents being the leading cause; 10.1% showed neuro-ophthalmic manifestations, primarily optic neuropathy.
  • Significant associations were found between brain contusions and optic neuropathy, as well as skull fractures and trochlear nerve palsy, highlighting the importance of early neuro-ophthalmic assessments in head injury patients.*
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  • * A key sign of this disease is the presence of Kayser-Fleischer rings, which are deposits of copper around the cornea of the eye.
  • * These rings are crucial for diagnosing Wilson's disease and highlight the disease's relationship with copper buildup in the body.
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  • Cystic hygromas are congenital lymphatic anomalies mostly found in young children, but rare cases can appear in older kids and at unusual sites like the chest wall.
  • Two cases were discussed: a 14-year-old and a 1-year-old, both with atypical swellings that were diagnosed through thorough examinations and imaging; they both successfully underwent surgery with no complications.
  • A comprehensive approach combining patient history, clinical assessment, imaging, and pathology is key for diagnosing cystic hygromas, which should be considered when evaluating any childhood swelling, despite their rarity.
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Objective: There is a paucity of data assessing the severity of coronavirus disease 2019 (COVID-19) infection and feto-maternal outcomes in pregnant women in Nepal, especially during the third wave of the pandemic with the Delta variant. This study aimed to severity as well as maternal-fetal outcomes among pregnant women with COVID-19 infection.

Methods: In this cross-sectional study carried out amongst COVID-19 positive pregnant women visiting our institution for 6 months from January through June 2022, data surrounding COVID-19 severity and fetal outcomes were collected in a structured questionnaire.

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Introduction And Importance: Outflow tract disorders are uncommon causes of primary amenorrhea. Transverse vaginal septum (TVS) is a rare cause of outflow tract obstruction.

Case Presentation: A 15-year-old female presented to us with severe abdominal pain.

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In developing countries, VVF mainly occurs due to obstructed labor unlike developed countries where common causes are radiotherapy and malignancy. Due to social taboos, patients do not seek medical attention for problems like urinary incontinence and dysuria, thus presenting very late.

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Ondine's curse is a rare condition in which breathing is preserved while awake, but there is absence of autonomic control of ventilation. It is a potentially fatal complication that may result rarely from surgery in posterior fossa in area close to respiratory centers. We describe a patient with posterior fossa hemangioblastoma who underwent subtotal resection via telovelar approach and developed acquired Ondine's curse postoperatively.

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Locally prepared liquor, which is not standardized or regulated, though cheap can contain various toxic ingredients and even may be fatal. We report a case series of four adult males who died within 18.5 h due to the effect of local liquor consumption in a hilly district of Gandaki Province of Nepal.

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Introduction: Scrub Typhus (ST) is an acute febrile illness caused by obligate intracellular bacteria of the family Rickettsia. It is often unrecognized and neglected but prevalent in tropical regions of endemic areas. The tragedy behind this diagnostic dilemma is non-specific clinical signs and symptoms, limited awareness, unavailability of diagnostic facilities, and low index of suspicion among the physicians.

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Introduction: Brucellosis is the commonest zoonotic disease worldwide and a common public health problem in Nepal. Because of the highly variable clinical presentation and non-specific manifestations, it remains a big challenge for clinicians from developing countries. Brucellosis has a tropism for the reticuloendothelial system, the liver is frequently involved.

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Background: is a rare cause of nosocomial infection in humans. These organisms are capable of biofilm production and are intrinsically resistant to commonly used antibiotics, leading to high rates of morbidity and mortality. may very rarely cause postneurosurgical infection.

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Dentigerous cysts are seen in the maxillary canine and third molars. We report a case of dentigerous cysts invading the maxillary sinus, which was managed surgically by endoscopic-assisted transantral and transnasal approach.

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Neurosurgery in Nepal is now more than half a century old. Though Nepalese neurosurgical roots can be traced back to ancient times, modern services began in Nepal only after 1990 following the arrival of Dr. Upendra Devkota-the father of Nepalese neurosurgery.

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Introduction And Importance: Blunt traumatic injury to the genitourinary system is uncommon. Urinoma formation may occur in patients with blunt trauma after high grade renal injuries. In such cases, the presence of solitary kidney must be ruled out as it may affect treatment decisions.

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Dicephalus parapagus are conjoined twins with two separate heads. Proper identification helps in patient counseling and timely referral to specialist centers.

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Introduction And Importance: Hemangiomas of paranasal sinuses are rare. Unexpected hemangiomas of this region can bleed profusely leading to operative morbidity and mortality. Hemangiomas of paranasal sinuses may be associated with concha bullosa.

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Synopsis of recent research by authors named "Mitesh Karn"

  • - Mitesh Karn's recent research focuses on various critical health issues including neurological conditions, infectious diseases, and innovative medical solutions, reflecting a holistic approach to clinical medicine in Nepal.
  • - Key findings from his studies highlight the importance of early diagnosis and intervention in conditions like Sturge-Weber syndrome and the effective management of long COVID-related complications using low-cost solutions.
  • - Additionally, his work emphasizes the need for awareness and research on neglected diseases such as scrub typhus and brucellosis, aiming to address public health challenges in Nepal through comprehensive clinical studies.