Conceptual Developments of Aryldiazonium Salts as Modifiers for Gold Colloids and Surfaces.

Modified colloids and flat surfaces occupy an important place in materials science research due to their widespread applications. Interest in the development of modifiers that adhere strongly to surfaces relates to the need for stability under ambient conditions in many applications. Diazonium salts have evolved as the primary choice for the modification of surfaces.

The influence of gold(i) on the mechanism of thiolate, disulfide exchange.

The mechanism of gold(i)-thiolate, disulfide exchange was investigated by using initial-rate kinetic studies, 2D ((1)H-(1)H) ROESY NMR spectroscopy, and electrochemical/chemical techniques. The rate law for exchange is overall second order, first order in gold(i)-thiolate and disulfide. 2D NMR experiments show evidence of association between gold(i)-thiolate and disulfide.

The influence of zinc(II) on thioredoxin/glutathione disulfide exchange: QM/MM studies to explore how zinc(II) accelerates exchange in higher dielectric environments.

QM/MM studies were performed to explore the energetics of exchange reactions of glutathione disulfide (GSSG) and the active site of thioredoxin [Cys32-Gly33-Pro34-Cys35] with and without zinc(II), in vacuum and solvated models. The activation energy for exchange, in the absence of zinc, is 29.7 kcal mol(-1) for the solvated model.

An infrared spectroscopic based method for mercury(II) detection in aqueous solutions.

A new method that uses solid phase extraction (SPE) coupled with FTIR spectroscopy to detect Hg(II) in aqueous samples is described. The technique is envisioned for on-site, field evaluation rather than lab-based techniques. This paper presents the "proof of principle" of this new approach toward measurements of Hg(II) in water and identifies mass transport issues that would need to be overcome in order to migrate from a lab based method to field operation.

Luminescence, structural, and bonding trends upon varying the halogen in isostructural aurophilic dimers.

The preparation of three isonitrile complexes (p-tosyl)CH(2)NCAu(I)X (X = Cl, Br, and I) along with their structural, spectral, and computational characterization are reported. X-Ray crystallography reveals that these complexes all crystallize in the same space group, C2/c, and have closely related supramolecular structures. The three complexes exhibit crossed-dimer structures with short Au.

Novel metallamacrocyclic gold(I) thiolate cluster complex: structure and luminescence of [Au9(mu-dppm)4(mu-p-tc)6](PF6)3.

The structure of a novel metallamacrocyclic phosphine gold(I) thiolate cluster, [Au9(mu-dppm)4(mu-p-tc)6](PF6)3, where dppm = bis(diphenylphosphine)methane and p-tc = p-thiocresolate, is reported and shows AuAu attractions of approximately 3.0 A and gold(I) atoms linked to thiolate and phosphine ligands in distorted trigonal and nearly linear geometries.

Mu-biphenyl-2,2'-dithiolato-kappa2S:S'-bis[(triphenylphosphine-kappaP)gold(I)].

The reaction of ClAuPPh3 and 1,1'-biphenyl-2,2'-dithiol in the presence of trimethylbenzylammonium chloride and K2CO3 in a tetrahydrofuran/methanol solution gives the title complex, [Au2(C12H8S2)(C18H15P)2]. The molecule contains P-Au-S units which 'cross' with torsion angles of approximately 90 degrees [P-Au-Au-P = 86.23 (5) degrees and S-Au-Au-S = 95.

[Mu-o-phenylenebis(diphenylphosphine)-kappa2P:P']bis[chlorogold(I)], dppbz(AuCl)2.

The Au...

Formation of a cationic gold(I) complex and disulfide by oxidation of the antiarthritic gold drug auranofin.

The mechanism of action of auranofin, an antiarthritic gold(I) drug, is unknown, but several studies suggest that oxidation may be important for its biochemical effect. Bulk electrolysis studies on auranofin [(Et(3)P)Au(TATG); TATG = 2,3,4,6-tetraacetyl-1-thio-d-glucopyranosato] at +1.2 and +1.