Publications by authors named "Misumi Shinoda"
Background: Goblet cells, which contribute to mucosal defense and repair in the intestinal epithelium, are depleted in human and rodent colitis. The Notch signal pathway regulates the differentiation of intestinal stem cells into epithelial cells and inhibits the differentiation of secretory lineages, including goblet cells. The aim of our study was to clarify whether the blocking of the Notch pathway at an early stage of colitis would preserve goblet cells and facilitate the healing process in dextran sulfate sodium (DSS)-induced colitis in mice.
View Article and Find Full Text PDF[Antecedent medical imaging for the early detection of pancreas cancer].
Nihon Shokakibyo Gakkai Zasshi
August 2009
Article Synopsis
- A 62-year-old Japanese man was misdiagnosed with squamous cell carcinoma of the gallbladder, but autopsy revealed it was actually adenoendocrine cell carcinoma.
- He experienced symptoms like vomiting and abdominal pain, and his CT scan showed a large gallbladder tumor with metastases in nearby organs and lymph nodes.
- Despite initial chemotherapy with gemcitabine leading to tumor growth, a switch to docetaxel and cisplatin resulted in some tumor regression, but he declined further treatment and passed away 8 months later.
A 77-year-old male was admitted to our hospital for a bulky abdominal mass. He had a history of appendectomy under the diagnosis of appendiceal rupture 23 years previously. He also had received a radical lung resection for an early lung cancer 2 years earlier in another hospital.
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