Publications by authors named "Mistuaki Ishida"
JTO Clin Res Rep
August 2021
Article Synopsis
- Hypercalcemia, often seen in cancer, is typically linked to parathyroid hormone activation but can also be caused by other factors, as shown in a specific case.
- A 76-year-old man experienced hypercalcemia due to excessive production of 1,25-dihydroxyvitamin D resulting from a high-grade fetal lung adenocarcinoma, with the tumor and surrounding cells showing a key enzyme related to this overproduction.
- After surgically removing the lung tumor, the patient's calcium levels returned to normal, indicating that the cancer-induced 1,25-dihydroxyvitamin D overproduction was the main cause of his hypercalcemia rather than the usual PTH-related mechanisms.
