Clinical assessment of stereoscopic optic disc photographs for glaucoma: the European Optic Disc Assessment Trial.

Purpose: To determine the diagnostic accuracy of judging optic disc photographs for glaucoma by ophthalmologists.

Design: Evaluation of diagnostic test and technology.

Participants: A total of 243 of 875 invited ophthalmologists in 11 European countries.

Assessment of optic disc anatomy and nerve fiber layer thickness in ocular hypertensive subjects with normal short-wavelength automated perimetry.

Purpose: To compare optic disc topography and nerve fiber layer thickness in ocular hypertensive eyes and normal subjects.

Design: Prospective, case-controlled study.

Participants And Controls: One eye in each of 20 normal and 27 ocular hypertensive patients was enrolled.

Pulsatile ocular blood flow in patients with pseudoexfoliation.

Purpose: Pseudoexfoliation syndrome is one of the most frequent causes of open-angle glaucoma and is statistically significant associated with a high risk of hypertension, angina, myocardial infarction or stroke and retinal vein thrombosis. The aim of this study was to evaluate the pulsatile ocular blood flow (POBF) in pseudoexfoliation syndrome without (PEX) and with glaucoma (PEG).

Methods: Seventeen eyes with PEX, 17 with PEG and 11 normal eyes of age-matched patients were enrolled.

Scanning laser polarimetry (SLP) for optic nerve head drusen.

Optic nerve head drusen (ONHD) are either clinically invisible or clearly protruding from the disc, in the later case leading to the condition of an irregular, indistinct disc margin or a swollen disc on biomicroscopy. They also may cause visual field defects, even with slow progression. Scanning laser polarimetry (SLP) has been proposed as a rapid, objective and reproducible technology for retinal nerve fiber layer (RNFL) assessment and clinical studies have demonstrated that SLP can help to distinguish between normal and glaucomatous eyes, identify glaucoma suspects and correlates well with visual field defects.

Repair of a late-onset filtering bleb leak using a corneal graft shaped with an excimer laser.

A new method for repairing an area of late scleral necrosis and bleb leak after glaucoma-filtering surgery using mitomycin C (MMC) is described. In a 33-year-old female patient diagnosed with bilateral juvenile glaucoma, a bleb leak occurred 41 months after trabeculectomy with MMC in the left eye. A corneal stromal patch-graft shaped to the desired size using an excimer laser (Excimer-Laser-Corneal-Shaping-System, ELCS-S) was used to cover the scleral defect.

Diode laser transscleral cyclophotocoagulation for refractory glaucoma.

Purpose: To evaluate the efficacy of contact diode laser transscleral cyclophotocoagulation using different treatment parameters.

Methods: All eyes undergoing contact diode laser transscleral cyclophotocoagulation between April 1991 and September 1997 at our two institutions were enrolled. Success was defined as an intraocular pressure less than or equal to 22 mm Hg or absence of pain for poorly sighted and blind eyes.

Central retinal vessel trunk exit and location of glaucomatous parapapillary atrophy in glaucoma.

Objective: To evaluate whether the position of the central retinal vessel trunk exit on the lamina cribrosa spatially correlates with the location of parapapillary atrophy in glaucoma.

Design: Clinic-based, observational, cross-sectional study.

Patients: Color stereo optic disc photographs of 95 patients with primary or secondary open-angle glaucoma and 65 healthy persons were morphometrically evaluated.

Optical coherence tomography and scanning laser polarimetry in normal, ocular hypertensive, and glaucomatous eyes.

Purpose: To evaluate the relationship between visual function and retinal nerve fiber layer measurements obtained with scanning laser polarimetry and optical coherence tomography in a masked, prospective trial.

Methods: Consecutive normal, ocular hypertensive, and glaucomatous subjects who met inclusion and exclusion criteria were evaluated. Complete ophthalmologic examination, disk photography, scanning laser polarimetry, optical coherence tomography, and automated achromatic perimetry were performed.

Heidelberg retina tomography and optical coherence tomography in normal, ocular-hypertensive, and glaucomatous eyes.

Purpose: To evaluate optic disc and retinal nerve fiber layer (RNFL) appearance in normal, ocular-hypertensive, and glaucomatous eyes undergoing confocal scanning laser ophthalmoscopy and optical coherence tomography (OCT).

Design: Prospective, cross-sectional study.

Participants: Seventy-eight eyes of 78 consecutive normal (n = 17), ocular-hypertensive (n = 23), and glaucomatous subjects (n = 38) were enrolled.

Increasing sampling density improves reproducibility of optical coherence tomography measurements.

Purpose: Published series of peripapillary retinal nerve fiber layer (RNFL) measurements using optical coherence tomography (OCT) have sampled 100 evenly distributed points on a 360 degrees peripapillary circular scan. The goal of this study was to determine whether a four-fold increase in sampling density improves the reproducibility of OCT measurements.

Methods: Complete ophthalmic examinations, achromatic automated perimetry, and OCT imaging were performed in all patients.

Effect of pupillary dilation on retinal nerve fiber layer thickness as measured by scanning laser polarimetry in eyes with and without cataract.

Purpose: This study was conducted to evaluate the effect of pupillary dilation on retinal nerve fiber layer (RNFL) thickness as measured by scanning laser polarimetry (SLP) in cataractous and noncataractous eyes.

Methods: The study included 31 eyes of 31 consecutive patients (mean age, 62.5 +/- 14.

A slit-lamp needling filtration procedure for uncontrolled glaucoma in pseudophakic and aphakic eyes.

In one aphakic and one pseudophakic patient without previous filtration surgery, a transconjunctival needling procedure similar to that used for failed filtration procedures was performed to create a filtering bleb. In both cases, intraocular pressure was successfully lowered for 6 months until the occurrence of bleb encapsulation, which was relieved by transconjunctival needling. There were no complications.

Anterior chamber contamination during cataract surgery with intraocular lens implantation.

Purpose: To measure anterior chamber bacterial and fungal contamination at the beginning and end of cataract surgery with intraocular lens (IOL) implantation in a large series of patients and to determine the influence of preoperative treatment and operative technique on contamination.

Setting: Department of Ophthalmology, County Hospital of Salzburg, Austria.

Methods: This prospective study comprised 700 consecutive patients having planned cataract extraction (511 phacoemulsification, 189 extracapsular cataract extraction [ECCE]).

[Endogenous candida endophthalmitis: a new therapy].

A thirty-year-old patient underwent an extensive abdominal surgery because of a precancerosis due to a colitis ulcerosa. An accompanying smoldering panuveitis led under immunosuppressive therapy to the loss of sight of one eye. Only an increasing vitritis of the second eye allowed the diagnosis of an endogenous Candida endophthalmitis (ECE) following a vitrectomy.