Testotoxicosis without Testicular Mass: Revealed by Peripheral Precocious Puberty and Confirmed by Somatic Gene Mutation.

: Testotoxicosis is an autosomal dominant form of limited gonadotropin-independent precocious puberty in boys. It is caused by a heterozygous constitutively activating mutation of the gene encoding the luteinizing/hormone receptor (LHR). Some twenty mutations of the gene have been reported.