A female patient in her middle childhood who was initially referred to us with congenital glaucoma was later diagnosed with congenital hereditary endothelial dystrophy. Due to progressive corneal thickening and haze, Descemet's stripping endothelial keratoplasty (DSEK) was performed consecutively in both her eyes. Postoperative follow-ups included evaluations of corneal thickness, intraocular pressure and disc assessment.
View Article and Find Full Text PDFPurpose: The purpose of this article was to evaluate the impact of sample collection order on the diagnostic yield of metagenomic deep sequencing (MDS) for determining the causative pathogen in infectious keratitis.
Methods: We performed a cross-sectional diagnostic test evaluation among subjects with infectious keratitis at Aravind Eye Hospital in Madurai, India. All subjects underwent corneal scrapings of the affected eye to obtain potassium hydroxide smear, Gram stain, bacterial culture, and fungal culture, in this order.
We report two cases of keratitis caused by a rare fungus species. Clinical presentation, identification, and management were studied. Both fungi were grown from corneal scraping and identified as and based on the microbiological techniques and DNA sequencing analysis.
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