Publications by authors named "Misra Sikha"

A female patient in her middle childhood who was initially referred to us with congenital glaucoma was later diagnosed with congenital hereditary endothelial dystrophy. Due to progressive corneal thickening and haze, Descemet's stripping endothelial keratoplasty (DSEK) was performed consecutively in both her eyes. Postoperative follow-ups included evaluations of corneal thickness, intraocular pressure and disc assessment.

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Article Synopsis
  • The study aimed to analyze the demographic, clinical, and microbiological characteristics of patients with Demodex-related blepharokeratoconjunctivitis (BKC) at a specialized eye care hospital over a period from 2016 to 2022.
  • It involved 83 patients, primarily under 40 years old, with common symptoms including good visual acuity and unilateral disease presentation, while cylindrical dandruff was the most frequent observation.
  • Treatment with tea tree oil and lid scrubs was successful in 90% of cases, and the study highlighted the importance of microscopic evaluation for diagnosis, especially in recurrent cases requiring additional management like topical steroids for inflammation.
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Purpose: The purpose of this article was to evaluate the impact of sample collection order on the diagnostic yield of metagenomic deep sequencing (MDS) for determining the causative pathogen in infectious keratitis.

Methods: We performed a cross-sectional diagnostic test evaluation among subjects with infectious keratitis at Aravind Eye Hospital in Madurai, India. All subjects underwent corneal scrapings of the affected eye to obtain potassium hydroxide smear, Gram stain, bacterial culture, and fungal culture, in this order.

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We report two cases of keratitis caused by a rare fungus species. Clinical presentation, identification, and management were studied. Both fungi were grown from corneal scraping and identified as and based on the microbiological techniques and DNA sequencing analysis.

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