Publications by authors named "Mislav Kovacic"

Scent rolling, a behaviour observed in various large carnivores like wolves, entails the animal lowering its chin and neck towards a scent, followed by rubbing the head, neck, shoulders, and back into it. This behaviour is prevalent among wolves exposed to diverse scents, though its exact purpose remains uncertain. In this study, captive wolves at Osijek Zoo responded differently to odours during olfactory enrichment sessions.

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  • * The study found no significant differences in the size or concentration of serum EVs between healthy and infected dogs, but a higher number of proteins from Canis lupus were detected in infected dogs, with 211 proteins identified across both groups.
  • * Specific proteins related to the immune response and cellular processes were enriched in EVs from infected dogs, suggesting that these EVs play a role in the disease's progression and immune response mechanisms.
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  • Dilated cardiomyopathy (iDCM) is a significant disease affecting both dogs and humans, being the second leading cause of heart failure in dogs and can lead to sudden cardiac death.
  • This study compared the plasma metabolome of 12 dogs with iDCM to 8 healthy dogs, utilizing advanced mass-spectrometry techniques to identify 272 metabolites.
  • Findings revealed notable changes in metabolite concentrations (like amino acids and lipids) associated with iDCM, paving the way for better understanding and monitoring of this condition in the future.
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Cow serum proteome was evaluated by three different complementary approaches in the control group, subclinical and clinical mastitis in order to possibly find differential protein expression useful for a better understanding of the pathophysiology of mastitis as well as for an early diagnosis of the disease. The systemic inflammatory and oxidative stress response in cows with subclinical and clinical mastitis were observed. The collected evidence shows a differential protein expression of serpin A3-1, vitronectin-like protein and complement factor H in subclinical mastitis in comparison with the control.

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