Publications by authors named "Misato Tsubokura"

We herein report a case of peripheral blood stem cell transplantation (PBSCT) involving a donor with EDTA-induced pseudothrombocytopenia (PTCP). The apheresis product was inspected for 24 h and there was no platelet clumping or thrombocytopenia. In the first 14 months after PBSCT, there has been no transfer of PTCP symptoms.

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Background: Cell-free and concentrated ascites reinfusion therapy (CART) is a strategy for improving various intractable symptoms due to refractory ascites, including hypoalbuminemia. CART has recently been applied in the treatment of cancer patients. This study was performed to assess the safety of CART in a single cancer institute.

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The chylous turbidity of blood samples is one of the causes of false-high hemoglobin (Hgb) concentration measurements by the colorimetric method, which has been widely applied in hematology analyzers. In such cases, additional manual procedures are required to correct Hgb concentrations. We therefore examined the effectiveness of an optical method for measuring Hgb concentrations in samples with chylous turbidity using Hgb-O in the reticulocyte channel equipped in XN-series analyzers (Sysmex, Kobe, Japan).

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Article Synopsis
  • - The study investigates how monitoring peripheral blood hematopoietic progenitor cells (HPCs) can predict the timing for autologous peripheral blood stem cell harvest (APBSCH) by analyzing data from 84 patients.
  • - It was found that specific HPC count thresholds (21/μL the day before collection and 41/μL the day of collection) are strong indicators of collecting sufficient CD34-positive cells, which are crucial for the procedure.
  • - The research concludes that HPC counts from both the day before and the day of the collection provide valuable guidance for successfully timing APBSCH.
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We reviewed blood product use in 729 consecutive allogeneic hematopoietic cell transplantation (allo-HCT) recipients at our center to assess the volume of red blood cells (RBCs) and platelets required after allo-HCT. The median number of bags required by day 30 was 4 for RBCs (range 0-22) and 9.5 for platelets (0-53).

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