Prevalence and clinical features of interstitial lung disease in patients with psoriasis.

Background: Despite the autoimmune nature of psoriasis, the potential association between psoriasis and interstitial lung disease (ILD) remains underexplored. This study aimed to investigate the frequency and clinical features of ILD in patients with psoriasis and propose a new conceptual framework of "ILD associated with psoriasis".

Methods: A retrospective analysis of 117 patients with psoriasis was conducted, excluding those without chest imaging prior to methotrexate or biologic use and those with other comorbidities leading to ILD.

[Anterior Mediastinal Dermoid Cyst with Enlarging Tendency:Report of a Case].

A 36-year-old woman referred to our hospital for treatment of a mediastinal tumor. Contrast computed tomography (CT) scan was revealed a 31×21×25 mm mass in the anterior mediastinum, with low contrast, clear border, and a tendency to increase. On magnetic resonance imaging( MRI) examination, the anterior mediastinal tumor showed homogeneous high signal intensity on T1-weighted images and a combination of high and low signal intensities on T2-weighted images.

Regional variations and sex-related differences of stiffness in human tracheal ligaments.

Purpose: There have been numerous studies focused on the stiffness of tracheal cartilage. However, no research has been conducted specifically on the annular ligament, nor have any regional differences in the annular ligament been identified. The purpose of this study was to investigate the stiffness of the ligaments present between the thyroid, cricoid and tracheal cartilages.

[Mixed Squamous Cell and Glandular Papilloma in the Peripheral Lung:Report of a Case].

Pulmonary papillary tumors are usually occur in the upper respiratory tract, and solitary papilloma in the peripheral lung are extremely rare. Lung papillomas sometimes show the elevation of tumor marker or F18-fluorodeoxyglucose (FDG) uptake, and are difficult to distinguish from lung carcinoma. Here we report a case of mixed squamous cell and glandular papilloma in the peripheral lung.

Perpendicular implantation of porcine trachea extracellular matrix for enhanced xenogeneic scaffold surface epithelialization in a canine model.

Objective: The availability of clinically applied medical materials in thoracic surgery remains insufficient, especially materials for treating tracheal defects. Herein, the potential of porcine extracellular matrix (P-ECM) as a new airway reconstruction material was explored by xenotransplanting it into a canine trachea.

Methods: P-ECM was first transplanted into the buttocks of Narc Beagle dogs ( = 3) and its overall immuno-induced effects were evaluated.

Dual Image Navigation to Secure Surgical Margins in Thoracoscopic Segmentectomy.

Purpose: Video-assisted thoracoscopic surgery (VATS) segmentectomy is being increasingly used for the management of non-small cell lung cancer. For non-palpable lesions, surgeons frequently find difficulty in ensuring a sufficient surgical resection margin.

Objective: The purpose of this study was to evaluate the role of intraoperative dual image navigation in combination with the infrared thoracoscopy with intravenous injection of indocyanine green (IRT-ICG) method and intraoperative computed tomography (CT) in detecting oncological margins.

Segmentectomy Provides Comparable Outcomes to Lobectomy for Stage IA Non-small Cell Lung Cancer with Spread through Air Spaces.

This study aimed to compare the recurrence-free survival (RFS) and overall survival (OS) among wedge resection (non-anatomical resection), segmentectomy and lobectomy for pathological stage IA non-small cell lung cancer (NSCLC) with spread through air spaces (STAS). Patients underwent surgical treatment for pathological stage IA NSCLC between January 1, 2005, and March 31, 2016, at our hospital. Surgical procedures were classified as lobectomy, segmentectomy, and wedge resection.

Regeneration of emphysematous lungs using gelatin sheets that release basic fibroblast growth factor.

Purpose: Basic fibroblast growth factor (bFGF) induces regeneration and neovascularization of the lungs. We conducted this study to demonstrate the regeneration of emphysematous lungs achieved by gelatin sheets that slowly release bFGF into the visceral pleura in a canine model.

Methods: Porcine pancreatic elastase was used to induce bilateral lower lobe pulmonary emphysema in dogs.

[Anomalous V2 Preoperatively Identified by Three-dimensional Computed Tomography in a Patient with Primary Lung Cancer of Right Upper Lobe].

A 61-year-old woman was found to have multiple ground-glass nodules( GGNs) in both lungs by chest computed tomography (CT) scan. The lesion of the right S2 contained a partial solid component and was suspected to be minimally invasive adenocarcinoma. Three-dimensional CT showed two anomalous V2s descending dorsally to the intermediate bronchus and draining into the inferior pulmonary vein.

[Surgical Approach for Treatment of Postoperative Bronchopleural Fistula and Pyothorax].

A bronchopleural fistula is a serious condition that can develop into pyothorax. The incidence of bronchopleural fistula depends on the surgical procedure. Bronchopleural fistulas are classified into early and late types based on the time of development following surgical intervention.

Safe pneumonectomy for locally advanced lung cancer after induction therapy.

Purpose: To assess the safety and long-term outcomes of pneumonectomy after IT (IT-Pn) versus upfront pneumonectomy without IT (U-Pn) for locally advanced non-small-cell lung cancer (NSCLC).

Methods: We reviewed the clinical records of 69 patients who underwent pneumonectomy as U-Pn (n = 30) or IT-Pn (n = 39) between 2000 and 2019 at our institution, RESULTS: U-Pn included patients with pathological N0 (n = 13), N1 (n = 11) and N2 (n = 6). Among the patients treated with IT-Pn, 18 had pathological N0 (including 7 with complete responses), 5 had N1, 14 had N2, and 2 had N3.

[Empyema Secondary to Percutaneous Liver Drainage via Thoracic Cavity for Hepatic Abscess].

Percutaneous liver drainage is associated with few complications. We report a case of empyema secondary to passage of a drain through the chest cavity in a patient treated with percutaneous liver drainage for hepatic abscess. A 72-year-old man was diagnosed with a liver abscess and underwent percutaneous liver drainage via the 7th intercostal space.

Constant-rate intravenous infusion of indocyanine green leading to high fluorescence intensity in infrared thoracoscopic segmentectomy.

Objectives: The purpose of this study was to determine whether or not fluorescence could be increased by administering indocyanine green at a constant rate, thus stabilizing its blood concentration.

Methods: In 20 consecutive patients undergoing segmentectomy, the dominant pulmonary arteries were ligated, blocking blood in the target segment. Fluorescence intensity was then observed using different indocyanine green administration methods under infrared thoracoscopy.

[Thoracoscopic Diaphragmatic Stitching for the Catamenial Pneumothorax].

A 46-year-old woman experienced an initial episode of right-sided spontaneous pneumothorax at the time of menstruation. The findings of thoracoscopic examination suggested catamenial pneumothorax. Thoracoscopic surgery revealed multiple blueberry spots on the diaphragm.

Elastofibroma developing at the subscapular port site after thoracoscopic surgery: first case report.

In recent years, the number of cancer patients who undergo endoscopic surgery has been increasing, and port-site recurrence is becoming a more common complication. A 66-year-old woman underwent thoracoscopic left lower lobectomy with lymph node dissection for pT1aN0M0 adenocarcinoma of the lung. Six years after surgery, CT revealed a subscapular tumor measuring 3 cm at the site of the surgical port wound.

Blood pressure during pregnancy is a useful predictive maker for hypertension and dyslipidemia later in life, a population-based, cross-sectional study.

Objective: Pregnancy is an opportunity for women to become aware of their risk of cardiovascular disease (CVD), because physiologic responses to dynamic hemodynamic changes can be observed during pregnancy. Accordingly, we hypothesized that blood pressure levels during pregnancy may be associated with the risk of CVD later in life.

Study Design: We used data from the Iwaki Health Promotion Project and designed a population-based, cross-sectional study.

Role of surgery in multi-modality treatment for carcinomatous pleuritis in patients with non-small cell lung cancer.

Objective: To evaluate the role of surgery in the treatment of the patients with non-small cell lung cancer with pleural dissemination.

Methods: The clinical records of 25 patients (mean age 69 years) diagnosed with carcinomatous pleuritis during a thoracotomy by pathological examination and followed by surgery between 1994 and 2012 were reviewed. The treatment modality, including surgery, the clinicopathologic characteristics and 5-year survival were analyzed.

Clinical trial of video-assisted thoracoscopic segmentectomy using infrared thoracoscopy with indocyanine green.

Objectives: The maintenance of a good surgical view is mandatory in video-assisted thoracoscopic surgery (VATS). For routine segmentectomy, it is necessary to re-inflate the lung in order to identify the intersegmental line. However, such re-inflation can occasionally obstruct the surgical view.

Clinical trial of new methods for identifying lung intersegmental borders using infrared thoracoscopy with indocyanine green: comparative analysis of 2- and 1-wavelength methods.

Objectives: Infrared thoracoscopy is a new method of identifying lung intersegmental borders. This study compared the efficacy of 2- and 1-wavelength infrared thoracoscopy.

Methods: A total of 30 consecutive patients who underwent segmentectomy were evaluated by these methods (2-wavelength method, 10 patients; 1-wavelength method, 20 patients).

Biomarkers as prognostic factors for cN2 or 3 non-small cell lung cancer treated by induction chemoradiotherapy and surgery.

Background: We have reported promising results of surgery after induction chemoradiotherapy (carboplatin-taxane, 50 Gy radiation) for cN2,3 non-small cell lung cancer (NSCLC). In order to understand the underlying mechanism, expression of excision repair cross-complementing 1 (ERCC1), class III β-tubulin (tubulin), thymidylate synthase (TYMS), and ribonucleotide reductase M1 (RRM1) were investigated.

Patients And Methods: Immunohistochemistry was performed in 45 patients with cN2,3 NSCLC, but only in twelve pathologically-complete response cases to evaluate intratumoral expression of these biomarkers.

[Predictor of intrathoracic lymph node metastasis in peripheral non-small cell lung cancers 20 mm or less in greatest dimension].

Purposes: To assess the independent predictor of lymph node metastasis( LNM) in peripheral smallsized non-small cell lung cancers (NSCLCs), we conducted a clinicopathologic analysis of patients with small-sized NSCLCs with and without intrathoracic LNM.

Methods: We retrospectively studied 213 patients who had undergone surgical resection of NSCLCs 20 mm or less in diameter. Categories of patient characteristics were divided into 2 groups based on clinicopathologic features, and the incidence of LNM was compared.

Prognostic factors in patients after lobectomy for p-T1aN0M0 adenocarcinoma.

Objectives: The seventh edition of the TNM Classification of Malignant Tumours was published in 2009. This study was conducted to investigate the prognostic factors of p-T1aN0M0 pulmonary adenocarcinoma, which is the earliest stage defined in the new TNM classification.

Methods: We retrospectively studied 122 patients who underwent lobectomy at our institution for p-T1aN0M0 adenocarcinoma, as re-categorized in the seventh TNM classification.

[Prognosis of surgically treated large cell neuroendocrine carcinoma].

Large cell neuroendocrine carcinoma (LCNEC) is a relatively rare tumor in malignant lung neoplasms. The prognosis of LCNEC is poor and there is no consensus on the treatment for LCNEC. We report our retrospective assessment of 11 patients of LCNEC from 1999 to 2008.

Preoperative hypoalbuminemia is a risk factor for late bronchopleural fistula after pneumonectomy.

Background: Pneumonectomy is still a high-risk surgical procedure. Postpneumonectomy bronchopleural fistula is an especially severe complication with a high mortality rate. Although several reports have discussed risk factors for early bronchopleural fistula after pneumonectomy, only a few have reported them for late bronchopleural fistula.