Reconstruction of the Reaction of Andalusicin Lantibiotic Modification by Lanthionine Synthetase AncKC in a Heterologous Escherichia coli System.

The increasing resistance of microorganisms to antibiotics makes it a necessity that we search for new antimicrobial agents. Due to their genetically encoded nature, peptides are promising candidates for new antimicrobial drugs. Lantipeptide andalusicin exhibits significant antimicrobial activity against Gram-positive bacteria, making it a promising scaffold for the development of DNA-encoded libraries of lantibiotics.

Bioengineering the Antimicrobial Activity of Yeast by Recombinant Thanatin Production.

The global spread of antibiotic resistance marks the end of the era of conventional antibiotics. Mankind desires new molecular tools to fight pathogenic bacteria. In this regard, the development of new antimicrobials based on antimicrobial peptides (AMPs) is again of particular interest.

Creation of Recombinant Biocontrol Agents by Genetic Programming of Yeast.

Bacterial infections caused by antibiotic-resistant pathogens pose an extremely serious and elusive problem in healthcare. The discovery and targeted creation of new antibiotics are today among the most important public health issues. Antibiotics based on antimicrobial peptides (AMPs) are of particular interest due to their genetically encoded nature.

Metals and metalloids in Antarctic krill and water in deep Weddell Sea areas.

The study on the concentration of trace elements in Antarctic krill and in water in the deep areas of the Atlantic sector of the Antarctic was performed. Concentrations of 22 trace elements were studied to determine their spatial distribution in krill, and to assess the accumulation ability of the krill against 8 of them. The trace elements concentration in krill diminished in the following order: Fe > Cu > Zn > Bа > B > Se > As > Cr > Ni > Ag > Li > Mn > V > Mo > Cd > Co > Hg > Be.

Po in Сrimean salt lakes.

This paper presents the results of radioecological monitoring study of natural radionuclide Po in 11 lakes located in different regions of the Crimean peninsula. These investigations of the Crimean salt lakes were conducted for the first time in the history. The main objectives of this work were: to determine the features of the Ро behavior in the salt lakes ecosystems, as well as calculation of the doses received by the lakes hydrobionts from α-radiation of absorbed Po.