Challenges faced by the Iranian health system in containing COVID-19: insights from a conventional content analysis.

Background: The COVID-19 pandemic is a global crisis, and health systems worldwide have faced numerous challenges in containing it. This study aimed to identify the challenges faced by the Iranian health system in controlling the COVID-19 pandemic.

Methods: A conventional content analysis approach was employed in this qualitative study.

The miRNA-mRNA Regulatory Network in Human Hepatocellular Carcinoma by Transcriptomic Analysis From GEO.

Background: Bioinformatics analysis of hepatocellular carcinoma (HCC) expression profiles can aid in understanding its molecular mechanisms and identifying new targets for diagnosis and treatment.

Aim: In this study, we analyzed expression profile datasets and miRNA expression profiles related to HCC from the GEO using R software to detect differentially expressed genes (DEGs) and differentially expressed miRNAs (DEmiRs).

Methods And Results: Common DEGs were identified, and a PPI network was constructed using the STRING database and Cytoscape software to identify hub genes.

Validation and reliability assessment of the Persian Adaptation of the Interprofessional Team Collaboration Scale II (P-AITCS-II) for Iranian healthcare providers.

The primary objective of this study was to perform a psychometric evaluation of the Persian adaptation of the Assessment of Interprofessional Team Collaboration Scale (P-AITCS-II). This methodological study aimed to assess the validity and reliability of the AITCS-II for practitioners within the Iranian healthcare context. Data were collected from a sample of 230 Iranian healthcare providers between May and June 2024.

Ultra-processed food intake in relation to metabolic health status in Iranian adolescents with overweight and obesity.

Background: Many studies have explored the association between food intake and metabolic health. However, research on the association of consuming ultra-processed foods (UPFs) and metabolic health in children and adolescents remains unclear. The objective of our study was to investigate the relation between UPFs consumption and metabolic health status in Iranian adolescents with overweight/obesity.

High-Dose Epidermal Radionuclide Therapy with Re (Rhenium) Resin in a Patient with Multiple Actinic Keratoses.

 High-dose epidermal radionuclide therapy using a nonsealed Re (Rhenium) resin is an alternative treatment option for nonmelanoma skin cancer. In this case study, we present the possible use of this therapy in a patient with multiple actinic keratosis (AK), which is a precancer of the skin.  A 55-year-old male was presented in our department with multiple AK, located on the cheek, temporal, and frontal area, with 1, 1, 2.

Night Interruption with Red and Far-Red Light Optimizes the Phytochemical Composition, Enhances Photosynthetic Efficiency, and Increases Biomass Partitioning in Italian Basil.

Controlled environment agriculture is a promising solution to address climate change and resource limitations. Light, the primary energy source driving photosynthesis and regulating plant growth, is critical in optimizing produce quality. However, the impact of specific light spectra during night interruption on improving phytochemical content and produce quality remains underexplored.

MicroRNA-146 family: Molecular insights into their role in regulation of signaling pathways in glioma progression.

Glioma is a highly lethal brain cancer in humans. Despite advancements in treatment, the prognosis for patients remains unfavorable. Epigenetic factors, along with their interactions and non-coding RNAs (ncRNAs), are crucial in glioma cells' development and aggressive characteristics.

Dual molecular tweezers extending from a nanohoop.

The field of nanohoops is mature enough that synthetic protocols exists to tune their size, composition (incorporation of heteroaromatic building blocks), connectivity ( linkages), and solubility in different media (hydrophobic hydrophilic). Here, we report an additional dimension incorporating the concept of fullerene tweezers into a nanohoop. The resulting hybrid nanohoop is highly strained at 77 kcal mol, possesses a quantum yield of 0.

Comparison of whole-body 18F-FDG-PET/CT with 18F-FDG-PET/CT limited to skull base to upper abdomen for primary staging of lung cancer - a retrospective explorative analysis.

The gold standard for ruling out distant metastases as part of primary staging in lung cancer is whole-body F-FDG-PET/CT, but this method is resource-intensive. Recent evidence suggests that examining only the thorax and upper abdomen may be sufficient 1 2 3. If a limited F-FDG-PET/CT approach proves effective for proper staging, it could lead to quicker examinations and reduced radiation exposure.

Therapeutic effects of acyclovir and acyclovir-clobetasol nanofibers vs. cream formulation for recurrent herpes labialis.

Objectives: This study aims to compare the therapeutic effects of acyclovir nanofiber and acyclovir-clobetasol nanofiber formulations with their non-nano formulations (cream formulation) on recurrent labial herpes.

Materials And Methods: Eighty patients with labial herpes lesions were divided into four groups, each receiving one of the following treatments: acyclovir-clobetasol nano patch, acyclovir-clobetasol cream, acyclovir nano patch, or acyclovir cream. Pain levels and recovery times were assessed.

The relationship between the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet and metabolic health status in adolescents with overweight and obesity: results from a cross-sectional study in Iran.

Few studies investigated the association between Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet and metabolic health status, particularly among adolescents. The present study was designed to investigate the association of MIND diet with metabolic health status in Iranian adolescents with overweight/obesity. This cross-sectional study was done among 203 adolescents with overweight/obesity (12-18 years) in Isfahan, Iran.

Colpocephaly and corpus callosum dysgenesis in an adult: A rare case report.

Introduction: Colpocephaly, a midline anomaly, may be associated with agenesis of the corpus callosum. While prenatal diagnosis is possible, this malformation is rarely detected in adults and may be asymptomatic.

Case Presentation: We present a case of a 54-year-old male with Colpocephaly and dysgenesis of the corpus callosum, incidentally diagnosed during an emergency department visit.

The effect of guided group reflection on the ability and convenience of breaking bad news in pre-hospital emergency staff.

Background: Bad news refers to any information that create negative changes in a person's understanding or expectations of in present and future. Breaking Bad News (BBN) is a stressful task that may have disturbing effects on the professional performance and general health of the medical staff. Pre-hospital emergency staff often needs to deliver bad news to the patient or his family.

Identification of proteins' expression pathway and the effective miRNAs for the treatment of human papillomavirus-induced cervical cancer: in-silico analyses-experimental research.

Introduction: Cervical cancer is the fourth most common cancer in women. The risk factors for cervical cancer include human papillomavirus (HPV) infection, age, smoking, number of pregnancies, use of oral contraceptives, and diet. However, long-term HPV infection appears to be the main risk factor for developing cervical cancer.

Prevalence of Surgical Site Infection After Hip Arthroplasty; a Systematic Review and Meta-Analysis.

Introduction: One of the worrisome complications of hip arthroplasty is surgical site infection (SSI). This study aimed to investigate the prevalence of SSI after hip arthroplasty.

Methods: A comprehensive and systematic exploration was conducted across various international electronic databases, including Scopus, PubMed, and Web of Science, alongside Persian electronic databases such as Iranmedex and the Scientific Information Database (SID).

Exploring the relationship between adverse childhood experiences and HPV vaccination in a national sample of adults.

Background: Over 60 % of U.S. adults report adverse childhood experience (ACE), which correlate with risky health behaviors and lower utilization of healthcare preventive measures, potentially leading to chronic diseases in later life.

Innovative genetic scissor strategies and their applications in cancer treatment and prevention: CRISPR modules and challenges.

There are lots of gene editing tools for targeting genome sequences. Some are almost known, and most are a complete mystery and undiscovered. CRISPR/Cas editing tools have brought about a major revolution in medicine.

Associations between perceived cancer impact and measures of health behavior in survivors of childhood cancer.

Purpose: Perceived cancer impact (PCI) is the degree to which one feels cancer has impacted one's life. It is unknown if PCI is associated with health behaviors. The aim of this study is to determine associations between PCI and health behaviors in childhood cancer survivors.

Gut microbe-derived metabolites and the risk of cardiovascular disease in the METSIM cohort.

Background: An association between gut microbes and cardiovascular disease (CVD) has been established, but the underlying mechanisms remain largely unknown.

Methods: We conducted a secondary analysis of the cross-sectional data obtained from the Metabolic Syndrome in Men (METSIM) population-based cohort of 10,194 Finnish men (age = 57.65 ± 7.

Recent Advances in the Diagnosis of Alzheimer's Disease: A Brief Overview of Tau PET Tracers in Nuclear Medicine.

Dementia (the most common cause of Alzheimer's disease) is defined as a chronic or progressive syndrome with disturbance of multiple cortical functions, the most important of them including memory, learning capacity, comprehension, orientation, calculation, language, and judgement. These cognitive impairments affect the quality of life, behavior, and social relations. Techniques of nuclear medicine provide feasible ways to record the intracellular alterations of disease and deficiencies.