Publications by authors named "Mirza Nafeul Islam"
Article Synopsis
- Human T-cell leukemia virus 1 (HTLV-1) poses serious health risks, with limited treatment options, prompting research into modified versions of the natural compound galangin as a potential treatment.
- To enhance galangin's poor bioavailability and solubility, scientists employed various drug design techniques, including molecular docking and dynamics simulations, revealing structurally modified versions that bind strongly to the HTLV-1 protease.
- The best compounds demonstrated promising stability and efficacy, suggesting that further testing could lead to effective therapies against HTLV-1.
Colorectal cancer is the second leading cause of cancer-related deaths. In 2018, there were an estimated 1.8 million cases, and this number is expected to increase to 2.
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