The tight calorie control study (TICACOS): a prospective, randomized, controlled pilot study of nutritional support in critically ill patients.

Purpose: To determine whether nutritional support guided by repeated measurements of resting energy requirements improves the outcome of critically ill patients.

Methods: This was a prospective, randomized, single-center, pilot clinical trial conducted in an adult general intensive care (ICU) unit. The study population comprised mechanically ventilated patients (n = 130) expected to stay in ICU more than 3 days.

Effects of polyunsaturated fatty acid consumption in diabetic nephropathy.

The complex metabolic, vascular and inflammatory perturbations that characterize diabetes mellitus often lead to progressive albuminuria, renal injury and dysfunction (diabetic nephropathy [DN]), and diabetes is the leading cause of end-stage renal disease in the US and Europe. Diet has an important role in cardiometabolic disorders and its potential influence on DN is of interest. Fatty acids are a major source of energy, but in excess, fatty acids (particularly saturated fatty acids) can induce lipotoxicity.

Anti-inflammatory properties of omega-3 fatty acids in critical illness: novel mechanisms and an integrative perspective.

Introduction: Fish oil-based nutrition is protective in severe critical care conditions. Regulation of the activity of transcription factor NF-kappaB is an important therapeutic effect of the major omega-3 fatty acids in fish oil, eicosapentaenoic and docosahexaenoic acid (EPA and DHA).

Methods And Results: Using the articles obtained by a Pubmed research, this article reviews three aspects of NF-kappaB/inflammatory inhibition by fish oil.

Eating habits and quality of life of patients receiving home parenteral nutrition in Israel.

Background & Aims: Using the database of an infusion provider, we assessed the quality of life and the eating behavior of patients receiving long-term home parenteral nutrition (HPN).

Methods: Fifty-one patients were recruited during a 2-month period and anthropometric measurements, etiology of the disease and length of therapy were noted. A questionnaire including seven questions evaluating four functions was completed by a student by phone interview.

A diet enriched in eicosapentanoic acid, gamma-linolenic acid and antioxidants in the prevention of new pressure ulcer formation in critically ill patients with acute lung injury: A randomized, prospective, controlled study.

Background & Aims: Pressure ulcers are a significant burden in the ICU. Many factors have found to be associated with pressure ulcers including malnutrition. While it has been recognized that high protein diets decrease the incidence of pressure ulcers, the role of lipids as well as vitamins and antioxidants remains unclear.

WITHDRAWN: A diet enriched in eicosapentanoic acid, gamma-linolenic acid and antioxidants in the prevention of new pressure ulcer formation in critically ill patients with lung injury: A randomized, prospective, controlled study.

The Publisher regrets that this article is an accidental duplication of an article that has already been published in Clin. Nutr., doi:10.