Allergy is the result of genetic and environmental interactions, including time, route, and dose of food exposure in susceptible patients. Risk factors can be: 1) genetic and 2) environmental, and these, in turn, are divided into prenatal, perinatal and postnatal. Food allergy appears frequently and depends on multiple risk factors (genetic and environmental), which in turn are divided into: prenatal, natal and postnatal factors; They participate in the expression of the disease and clinical intervention is not possible in all cases.
View Article and Find Full Text PDFBackground: Sensitization to () is very frequent in the tropics, and particularly in Cuba, being a significant cause of allergic asthma. Allergen immunotherapy (AIT) with can be a therapeutic option, however, placebo-controlled clinical trials have not been reported.
Objective: To assess the therapeutic effect and safety of AIT for asthma using a standardized allergen vaccine of by subcutaneous route, in allergic asthmatic patients exposed and sensitized to this mite species.
Background: Peanut allergy is increasing at an alarming pace in developed countries. Peanut () is a common food in Cuba. Nevertheless, reported values of sensitization and symptom severity are usually low.
View Article and Find Full Text PDFBackground: Diagnostic options for immune reactions to mosquito bites are limited. In Cuba, IgE-mediated reactions are frequently related to Culex quinquefasciatus bite.
Objective: To determine the sensitivity and specificity of skin prick test with two doses of standardized extract in nitrogen protein units (PNU of Culex quinquefasciatus (BIOCEN, Cuba).
Background: Occupational allergies are becoming more frequent. The allergens present in the working environment of bakeries, such as mites, are not well identified despite being known risk factors of respiratory diseases.
Objectives: To isolate and identify the species of mites present in two bakeries in La Habana, Cuba, with high sensitization of mites on their workers.
Most Latin-American countries use subcutaneous immunotherapy (SCIT) extracts from the United States and Europe and sublingual immunotherapy (SLIT) from Europe, with the exception of Argentina, Brazil, Cuba and Mexico. The number of researches on immunotherapy (IT) in Latin America has increased extensively in the last years. Only few Latin American countries have their own guidelines on IT, and, in general, the economic resources for medical research on IT are still low in the area.
View Article and Find Full Text PDFBackground: Upper respiratory infections constitute an important cause of morbidity among pre-school children. In many cases the frequent occurrence of these processes represent an atopic manifestation.
Objective: To identify risk factors for the presentation of recurrent upper respiratory infections in pre-school children.
Background: Sensitization to allergens at the workplace is an essential factor for the development of occupational respiratory diseases.
Objetive: To determine the frequency of sensitization to mites and other occupational allergens in bakery workers, by skin prick test (PCP).
Methods: In this unpaired case-control study were included 17 workers, mean age 34 years (range 18-55), and the control group 14 patients, mean age 32 years (range 22-47), both predominantly male 76 % and 85 % respectively.
Background: Sensitization to three allergic mite species (Dermatophagoides pteronyssinus, Dermatophagoides siboney and Blomia tropicalis) from house dust in Cuba has been reported in different studies.
Objective: To assess allergic sensitization to these mites in a north coast area of Havana city.
Patients And Methods: A total of 210 allergic patients were selected, classified in two groups: from 1 to 14 years, and from 15 to 55 years.