Effect of acute isooxic hypercapnia on oxidative activity of systemic neutrophils in endotoxemic rabbits.

Introduction: Whether carbon dioxide (CO) affects systemic oxidative phenomena under conditions of endotoxemia is not sufficiently clarified. The study aimed to assess the impact of moderate acute hypercapnia on the respiratory burst of circulating neutrophils in mechanically ventilated endotoxemic rabbits.

Material And Methods: Twenty-four endotoxemic rabbits were mechanically ventilated with standard or CO-enriched gas mixture in order to obtain isooxic hypercapnia.