Dynamics of the erythropoiesis stimulating agent resistance index in incident hemodiafiltration and high-flux hemodialysis patients.

Hyporesponsiveness to erythropoiesis-stimulating agent therapy in dialysis patients is poorly understood. Some studies report an improvement in the erythropoiesis-stimulating agent resistance index (ERI) with hemodiafiltration (HDF) versus high-flux hemodialysis (HD). We explored ERI dynamics in 38,340 incident HDF and HD patients treated in 22 countries over a 7-year period.

A comparison of calcium acetate/magnesium carbonate and sevelamer-hydrochloride effects on fibroblast growth factor-23 and bone markers: post hoc evaluation from a controlled, randomized study.

Background: Different phosphate binders exert differing effects on bone mineral metabolism and levels of regulating hormones. The objective of this post hoc evaluation of the CALcium acetate MAGnesium carbonate (CALMAG) study was to compare the effects of calcium acetate/magnesium carbonate (CaMg) and a calcium-free phosphate binder, sevelamer-hydrochloride (HCl), on serum levels of fibroblast growth factor-23 (FGF-23) and markers of bone turnover.

Methods: This secondary analysis of the controlled, randomized CALMAG study, comparing the effect of CaMg and sevelamer-HCl on serum phosphorus (P), aimed to investigate the parameters described above.

Methanol poisoning--case report.

The aim of this paper is to present a case of 46-yr-old man, poisoned with methanol, treated with ethanol and haemodialysis. According to history, he was alcoholic, but without any others complaints, except mild hypertension. During the clinical course of methanol poisoning ECG revealed pathological Q wave and ST segment elevation in leads II, III, aVF, without increased cardiac enzymes activity.

[Hypertension in advanced age].

Hypertension occurs in above half of elderly patients with the most common type of hypertension being Isolated Systolic Hypertension (ISH). Because of very well documented benefits of ISH therapy in elderly patients attention must be paid to the successful therapy which means: appropriate arterial blood pressure measurement and correct diagnosis of ISH as well as individualization of therapy protocols in accordance with principle: "start low, go slow".