Hydrothermally processed 1D hydroxyapatite: Mechanism of formation and biocompatibility studies.

Recent developments in bone tissue engineering have led to an increased interest in one-dimensional (1D) hydroxyapatite (HA) nano- and micro-structures such as wires, ribbons and tubes. They have been proposed for use as cell substrates, reinforcing phases in composites and carriers for biologically active substances. Here we demonstrate the synthesis of 1D HA structures using an optimized, urea-assisted, high-yield hydrothermal batch process.

Apatite formation on nanomaterial calcium phosphate/poly-DL-lactide-co-glycolide in simulated body fluid.

Unlabelled: Simulated body fluid (SBF) is an artificial fluid which has ionic composition and ionic concentration similar to human blood plasma.

Purpose: This paper compares the interaction between the nanomaterial containing calcium phosphate/poly-dl-lactide-co-glycolide (N-CP/PLGA) and SBF, in order to investigate whether and to what extent inorganic ionic composition of human blood plasma leads to the aforementioned changes in the material.

Methods: N-CP/PLGA was incubated for 1, 2, 3, and 5 weeks in SBF.