Publications by authors named "Mirna Chahine"

Background/objectives: Women's health represents an integral component of public health. With breast cancer being the first worldwide and cervical cancer the fourth most common cancer among women, and while habits of intimate hygiene remain mediocre, it is crucial to address these issues. We aimed to evaluate the efficacy of a community-based intervention on the knowledge and preventive measures (K&P) of women toward breast cancer, cervical cancer, and intimate hygiene.

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  • - The study focused on the awareness of Lebanese men regarding prostate cancer (PC), utilizing a cross-sectional online survey to gather data on knowledge, attitudes, and practices related to the disease from 844 respondents between April and December 2021.
  • - Results showed that only 4.6% of participants had adequate knowledge about PC, with higher knowledge levels linked to educational attainment and prior awareness of PC. Approximately 40% displayed a positive attitude towards PC, influenced by factors like physician guidance and prior screenings.
  • - The study highlighted a significant relationship between age, income, and medical advice with improved practices for prostate exams and PSA testing, indicating an urgent need for tailored awareness campaigns to enhance KAP levels and ultimately manage prostate cancer
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  • * It involved 330 participants, revealing that while many had moderate to good attitudes towards BLS, a significant majority exhibited low knowledge and practice levels.
  • * The findings suggest that BLS training should be integrated as a core competency in healthcare programs to improve emergency response skills among future medical professionals.
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Objective: Smoking habits have widely changed over time; however, they remain a well-known fashion that risks people's health. In addition, nicotine addiction depends on the interplay between several factors. Our study aimed to understand the smoking habits and nicotine dependence in the Lebanese population before (September 2019) and during (June 2020) the economic crisis and COVID-19 pandemic.

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A school's commitment to promoting health extends beyond students' efforts to encompass parental involvement and must recognize the critical role of parents in enhancing overall student well-being. This study, conducted in 27 schools across Lebanon, assessed parents' awareness of their children's physical and mental health. A school health campaign involved direct medical interventions on 7184 students, followed by phone interviews with 3880 parents to compare their responses with the medical findings.

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In response to the diverse health challenges faced by today's youth and their extensive time spent in schools, we conducted a school health awareness campaign aimed at prioritizing well-being and academic performance. This analytical longitudinal study, spanning 27 schools in Lebanon, aimed to assess the impact of the awareness campaign on the health knowledge and practices of 5-, 8-, and 11-year-old students throughout pre- and post-intervention testing focused on general health and healthy habits, employing 11, 14, and 15 questions tailored to 5, 8, and 11 year olds, respectively. The questions covered various aspects, including sleep, personal and dental hygiene, nutrition, physical activity, addiction, security measures, and bullying.

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In this extensive study examining the health of 7184 school children aged 3 to 12 in 27 Lebanese schools, screenings involved medical evaluation and interviews, complemented by phone interviews with 3880 parents. Notably, one in two students received a medical referral, revealing prevalent issues such as dental cavities (33%), under-vaccination (25%), undetected vision problems (13%), abnormal growth (6%), underweight (27%), and overweight (33%). Additional concerns encompassed abnormal vital signs (3%), abuse signs (0.

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Background Context: Pedicle screw breach (PSB) is not uncommon following lumbar instrumentation, and in some instances, it may lead to vascular and/or neurologic complications. Previous literature suggested that screws crossing the vertebral midline on an anterior-posterior (AP) radiograph (or midsagittal on CT) are concerning for medial pedicle breach.

Objective: Our primary aim was to map out the safe zones (SZ) of bilateral pedicle instrumentation and their relationship at each lumbar vertebral level.

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Elevated blood levels of low-density lipoprotein cholesterol are a major cardiovascular risk factor, and cholesterol-lowering drugs are among the most prescribed drugs worldwide. Cancer is the second leading cause of death after cardiovascular diseases. The relationship between cancer development and statins intake is controversial, and there are no clear studies in Lebanon and the Middle East concerning this topic.

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Cardiovascular diseases (CVD) are the leading cause of death globally, followed by cancer. Angiotensin II contributes greatly to CVD pathogenesis, and Angiotensin II receptor blockers (ARBs) constitute a mainstay in hypertension and CVD management. However, the relationship between ARBs and cancer initiation is controversial, with no clear data in Lebanon.

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  • * CVD patients were older and showed better knowledge and attitudes towards CVD compared to non-CVD individuals; however, their practical application of that knowledge was lower.
  • * The study highlights the need for targeted educational campaigns in Lebanon to improve KAP about CVD, especially focusing on factors like educational level, region, and smoking habits, which significantly influence KAP scores.
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Background And Objectives: Hypertension (HTN) is a major health concern that leads to cardiovascular disease and premature death. Assessing HTN knowledge, attitude, and practice (KAP) is crucial for controlling HTN. This study aimed to determine HTN KAP among hypertensive patients residing in Lebanon.

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Background: Competency-based medical education has been emerging as a new educational model for learning. The development of medical education in Middle Eastern countries lacks basic literature in the area of medical education, particularly competency-based medical education (CBME).

Aim: Our objective is to validate a brief/rapid scale that informs us on the current perception of the acquiring of competencies of medical students and graduates from the Lebanese University, Lebanon.

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Objective: The aim of this study was to determine the accuracy of the PHILIPS DL8760, an oscillometric blood pressure (BP) measuring device designed for self-measurement in the general population according to the European Society of Hypertension International Protocol (ESH-IP) revision 2010.

Participants And Methods: The PHILIPS DL8760 measures BP at the brachial level. The validation was performed in 33 subjects.

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Short telomere length (TL) is associated with atherosclerotic cardiovascular disease (ACVD) and other age-related diseases. It is unclear whether these associations originate from having inherently short TL or a faster TL attrition before or during disease development. We proposed the blood-and-muscle model to assess TL dynamics throughout life course.

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  • Cardiovascular diseases (CVDs) are a significant health issue in developing countries, with strong links to indoor and outdoor pollution, though research results have been mixed.
  • A national study in Lebanon assessed the prevalence of CVD and its association with pollution exposure, alongside various sociodemographic and health factors.
  • Findings suggest that both indoor and outdoor pollution increase the risk of CVD, with a 44% higher risk for each additional pollution exposure, highlighting the need for public awareness and action to reduce pollution levels.
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There is limited epidemiologic data on hypertension (HTN) in Lebanon. This study aimed to determine the prevalence and associated risk factors of HTN in the adult Lebanese population and evaluate the association between dietary and psychological factors on systolic blood pressure (SBP). Cross-sectional analyses were conducted using a multistage cluster sample across Lebanon.

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Aim: Heat shock protein 60 (Hsp60) is a mediator of stress-induced vascular smooth muscle cell (VSMC) proliferation. This study will determine, first, if the mitochondrial or cytoplasmic localization of Hsp60 is critical to VSMC proliferation and, second, the mechanism of Hsp60 induction of VSMC proliferation with a focus on modification of nucleocytoplasmic trafficking.

Methods And Results: Hsp60 was overexpressed in primary rabbit VSMCs with or without a mitochondrial targeting sequence (AdHsp60).

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Stroke is a disease related to high mortality and morbidity, particularly in developing countries. Some studies have linked self-reported indoor and outdoor pollution to stroke and mini-stroke, while some others showed no association. Our objective was to assess this association in Lebanon, a Middle Eastern developing country.

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  • Hypertension is linked to high mortality and morbidity, particularly in developing countries, and may be influenced by exposure to air pollution.
  • A national study in Lebanon assessed the relationship between living conditions related to air pollution and hypertension, identifying a dose-effect relationship where each additional pollution exposure increased the risk of hypertension by 15%.
  • The study suggests the need for interventions to raise awareness about air pollution's effects on health and emphasizes the importance of reducing pollution to lessen the healthcare burden.
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Background: Following the European Society of Hypertension International Protocol (ESH-IP) Revision 2010, QardioArm and Omron M6 Comfort IT oscillometric devices were evaluated in the general population and in patients with type II diabetes, respectively, for self-blood pressure (BP) measurement.

Methods: Both devices, QardioArm and Omron M6 Comfort, measure BP at the brachial level. The ESH-IP Revision 2010 includes a total number of 33 subjects.

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Objective: Two oscillometric devices, the Microlife WatchBP O3 and the Omron RS6, designed for self-blood pressure measurement were evaluated according to the European Society of Hypertension (ESH)-International Protocol (IP) Revision 2010 in the obese population.

Methods: The Microlife WatchBP O3 measures blood pressure (BP) at the brachial level and the Omron RS6 measures BP at the wrist level. The ESH-IP revision 2010 includes a total of 33 subjects.

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  • - Lebanon is facing a rise in coronary heart diseases (CHDs), similar to trends in other low- and middle-income nations, but prevention strategies could help mitigate this issue.
  • - A nationwide study found that 13.4% of Lebanese adults aged 40 and older have CHD, which appears earlier in life compared to developed countries, particularly affecting males more than females at younger ages.
  • - The study identifies key risk factors for CHD in Lebanon, including age, sex, economic status, hypercholesterolemia, hypertension, family history of cardiovascular diseases, and diabetes, which can inform targeted prevention efforts.
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Arterial hypertension is a leading risk factor for cardiovascular disease and stroke. This study aimed to assess the predictors of uncontrolled systolic and diastolic blood pressure (BP) in Lebanon among treated hypertensive individuals. The authors included 562 participants 40 years and older.

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