Publications by authors named "Mirjam Lingel"
Article Synopsis
- Over 50% of acute ischemic stroke (AIS) patients experience minor neurological deficits, raising questions about the effectiveness of intravenous thrombolysis (IVT), particularly noted in the PRISMS trial which showed no significant benefits for these patients.
- This study explored whether AIS patients with minor strokes could benefit from CTP-guided IVT, with the primary goal being to achieve good functional outcomes as measured by the modified Rankin Scale at 90 days.
- Out of 267 patients studied, IVT treatment led to better outcomes at 90 days, but the presence of CTP mismatch (indicating ineffective blood flow) did not significantly affect the functional outcomes, suggesting CTP mismatch isn't useful for guiding IVT decisions in
Background: Hypoglycemia in patients with diabetes mellitus, particularly type 1 can mimic acute ischemic stroke by causing focal neurological deficits. In acute ischemic stroke, the interpretation of emergency imaging including computed tomography with angiography and perfusion is crucial to guide revascularizing therapy including intravenous thrombolysis. However, different metabolic abnormalities and stroke mimics can cause focal hypoperfusion.
View Article and Find Full Text PDF