Impaired skin microcirculation in paediatric patients with type 1 diabetes mellitus.

Aims/hypothesis: We used Laser Doppler Fluximetry (LDF) to define "normal" endothelial function in a large cohort of healthy children and adolescents and to evaluate skin microcirculation in paediatric patients with type 1 diabetes mellitus.

Methods: LDF was performed in 102 healthy children (12.8 ± 3.