Electrospun nanofiber blend with improved mechanical and biological performance.

Background: Here, electrospun fibers based on a blend of polycaprolactone (PCL), poly(ethylene glycol) (PEG), and gelatin methacryloyl (GelMA) were developed. The careful choice of this polymer combination allowed for the preparation of a biomaterial that preserved the mechanical strength of PCL, while at the same time improving the hydrophilicity of the blended material and human osteoblast maturation.

Methods: The morphology, chemical structure, wettability, and mechanical properties before and after UV photocrosslinking were evaluated.