Ensuring Appropriate Representation in Artificial Intelligence-Generated Medical Imagery: Protocol for a Methodological Approach to Address Skin Tone Bias.

Background: In medical education, particularly in anatomy and dermatology, generative artificial intelligence (AI) can be used to create customized illustrations. However, the underrepresentation of darker skin tones in medical textbooks and elsewhere, which serve as training data for AI, poses a significant challenge in ensuring diverse and inclusive educational materials.

Objective: This study aims to evaluate the extent of skin tone diversity in AI-generated medical images and to test whether the representation of skin tones can be improved by modifying AI prompts to better reflect the demographic makeup of the US population.

Magnesium Deficiency and Cardiometabolic Disease.

Magnesium (Mg) has many physiological functions within the body. These include important roles in maintaining cardiovascular functioning, where it contributes to the regulation of cardiac excitation-contraction coupling, endothelial functioning and haemostasis. The haemostatic roles of Mg impact upon both the protein and cellular arms of coagulation.

How to design a hypertension treatment trial that informs care of older people with frailty: a survey of clinicians in Ireland and the UK.

Introduction: At all ages, randomised trials demonstrate lower mortality and cardiovascular disease incidence with blood pressure (BP) lowering. However, this may not generalise to older people with frailty. We aimed to determine the acceptability to clinicians of key aspects of trial designs using different BP targets and strategies to better manage hypertension in the context of frailty.