Publications by authors named "Miriam Sirianni"
It is well known that the observation of graspable objects recruits the same motor representations involved in their actual manipulation. Recent evidence suggests that the presentation of nouns referring to graspable objects may exert similar effects. So far, however, it is not clear to what extent the modulation of the motor system during object observation overlaps with that related to noun processing.
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- The study examines the link between social disadvantage and the onset of psychosis by analyzing the backgrounds of 278 patients experiencing their first episode compared to 226 healthy controls.
- It finds that significant social adversities in childhood, such as long-term parental separation or loss, increase the odds of developing psychosis by 2 to 3 times, while adult social disadvantages also show a strong correlation.
- The research highlights that experiencing social disadvantage in both childhood and adulthood contributes to a higher risk of psychosis, suggesting the importance of early social interventions.
Background: Cannabis use is associated with an increased risk of psychosis. One study has suggested that genetic variation in the AKT1 gene might influence this effect.
Methods: In a case-control study of 489 first-episode psychosis patients and 278 control subjects, we investigated the interaction between variation at the AKT1 rs2494732 single nucleotide polymorphism and cannabis use in increasing the risk of psychosis.