Publications by authors named "Miriam Rodriguez-Fernandes"

Article Synopsis
  • - This study investigates the presence of virulence genes in Klebsiella pneumoniae (KPC-KP) using whole-genome sequencing, highlighting the frequency of hypervirulent and hypermucoviscous strains.
  • - It finds that most strains of KPC-KP are capable of forming biofilms, with 90.9% showing this ability, particularly focusing on the international clonal group 258 (CG258).
  • - The research identifies a link between sequence type ST437 and lower biofilm production, indicating that KPC-KP with multiple virulence traits is spreading in Brazilian hospitals, contributing to infection rates.
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The release of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae to the environment is a public health issue worldwide. The aim of this study was to investigate the genetic background of genes encoding ESBLs in wastewater treatment plants (WWTPs) in São Paulo, southeastern Brazil. In 2009, during a local surveillance study, seven ESBL-producing Enterobacteriaceae strains were recovered from five WWTPs and screened for ESBL genes and mobile genetic elements.

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Enterotoxigenic Bacteroides fragilis (ETBF) is an important part of the human and animal intestinal microbiota and is commonly associated with diarrhea. ETBF strains produce an enterotoxin encoded by the bft gene located in the B. fragilis pathogenicity island (BfPAI).

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Introduction: causes gastroenteritis in humans and animals.

Case Presentation: In this study, both Shiga toxin-producing (STEC) and atypical enteropathogenic (EPEC) strains were identified in a stool sample from a healthy child, and they were serotyped as Shiga toxin-producing (STEC) ONT : H19 and atypical enteropathogenic (EPEC) O37 : H45.

Conclusion: This is the first report, to our knowledge, of a concomitant presence of diarrhoeagenic (DEC) strains in an asymptomatic child.

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Background: An outbreak of serogroup C meningococcal disease (MD) that involved employees from an oil refinery occurred in Paulínia, from March to June 2010, and spread to the community of Cosmópolis, both situated in São Paulo State, Brazil. The aim of this study was to describe the epidemiological and laboratory aspects, and the control measures that were implemented.

Methods: Descriptive and molecular epidemiological analysis was used to define the extent of the outbreak and the common risk factors among outbreak related cases.

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