Publications by authors named "Miriam Menacho Roman"
HOSPITAL-BASED HEALTH TECHNOLOGY ASSESSMENT OF A SCREENING RAPID TEST MTBI (GFAP AND UCH-L1 BLOOD BIOMARKERS) FOR MILD TRAUMATIC BRAIN INJURY.
Int J Technol Assess Health Care
December 2024
Unlabelled: The measurement of urinary sodium excretion provides valuable information about an individual's sodium balance and can help in the management of various medical conditions. However, the collection of 24-hour urine samples is subject to errors. Spot urine sodium (uNa) measurements are a reliable alternative to 24-hour urine collections for estimating urinary sodium excretion.
View Article and Find Full Text PDFIntroduction: Bronchiectasis is typically treated with inhaled antibiotics in clinical practice. However, there is a striking lack of standardised procedures for the preparation of noncommercial solutions. We used biochemical parameters to analyse the safety and tolerability of inhaled antibiotics in patients with bronchiectasis, and determined potential associations between the inhaled antibiotics used and adherence to the medications and quality of life.
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- - The study assessed the prevalence of 25-hydroxyvitamin D (25-(OH)D) deficiency among 33,601 patients, finding an overall deficiency rate of 48%, with males being more affected than females (53% vs. 46%).
- - It was discovered that 25-(OH)D deficiency was significantly influenced by age, with the highest rates in the oldest group (74-87 years) and more common in spring compared to other seasons.
- - Additionally, a weak association was found between 25-(OH)D levels and parathyroid hormone (PTH) levels, with increased PTH linked to low 25-(OH)D, as well as factors like female sex
The allele ε4 of the apolipoprotein E gene (APOE ε4) is the major genetic risk factor for non-dominantly inherited Alzheimer's Disease (AD). Current techniques for APOE ε4 carriers identification show good accuracy but have several disadvantages that limit its implementation in a clinical laboratory. These include the need for sample preprocessing, poor automation, low throughput, requirement of additional equipment, and high cost.
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- - The study aimed to determine the prevalence, incidence, and sex ratio of transsexualism in Madrid, analyzing data from 1,171 patients over an 8-year period.
- - The findings revealed a prevalence rate of 22.1 cases per 100,000 residents, with a higher rate among male-to-female (31.2) compared to female-to-male (12.9), leading to a sex ratio of approximately 2.2:1.
- - The higher prevalence in Madrid compared to other European countries may be attributed to easy access to gender identity services and a supportive social and legal environment.
Article Synopsis
- The study investigates the high prevalence of hyperandrogenism (HA) and polycystic ovary syndrome (PCOS) among female-to-male transsexuals (FMT) prior to starting cross-sex hormone therapy.
- Results show that nearly half of the participants had HA, with over a third diagnosed with PCOS, while more than a third exhibited signs of metabolic syndrome, which increases cardiovascular risks.
- The findings indicate a concerning association between HA, PCOS, and early signs of metabolic syndrome, highlighting potential long-term health implications for FMT individuals.