Publications by authors named "Miriam Lucke"
Article Synopsis
- Plasmids are tiny, movable pieces of DNA that help bacteria share useful genes, like those that make them resistant to medicine.
- Scientists have created a new tool called Deeplasmid that uses deep learning to identify plasmids from DNA sequences faster and more accurately than other methods.
- Deeplasmid was successfully tested on a fish disease-causing bacteria, identifying a new plasmid, which was later confirmed using a different sequencing method.
Beneficial rhizobacteria dwell in plant roots and promote plant growth, development, and resistance to various stress types. In recent years there have been large-scale efforts to culture root-associated bacteria and sequence their genomes to uncover novel beneficial microbes. However, only a few strains of rhizobacteria from the large pool of soil microbes have been studied at the molecular level.
View Article and Find Full Text PDFBackground: Our knowledge of natural genetic variation is increasing at an extremely rapid pace, affording an opportunity to come to a much richer understanding of how effects of specific genes are dependent on the genetic background. To achieve a systematic understanding of such GxG interactions, it is desirable to develop genome editing tools that can be rapidly deployed across many different genetic varieties.
Results: We present an efficient CRISPR/Cas9 toolbox of super module (SM) vectors.